Microglia dysfunction in those who experienced early life adversity prompts an aberrant stress response during adulthood that may be linked to mental illness.
A molecular process caused by the TREM2 gene mutation in the brain's microglia increases the risk of Alzheimer's disease, a new study reports.
The P522R gene variant increases expression levels of several microglia genes which are reduced in people with Alzheimer's disease.
Study identifies a novel neural circuit that regulates spatial learning and memory in the brain's hippocampal formation.
Long-term memory consolidation and short-term memory processes that occur during sleep do so at a cost to one another.
The extracts of certain plants long used by Native Americans as topical analgesics activate the KCNQ2/3 potassium channel. The compounds provide pain relief and prevent diarrhea.
Dopamine-controlled fan cells in the lateral entorhinal cortex are required for the formation of associative memories.
Piezo1 limits the potential of regulatory T cells (Treg) to mitigate autoimmune neuroinflammation. Inhibiting Piezo1 could lead to new treatments for autoimmune disorders like multiple sclerosis.
Lower serum levels of the sugar metabolite GlcNAc was associated with progressive disability and neurodegeneration in patients with multiple sclerosis.
N-acetylglucosamine, a simple sugar found in breast milk, promotes remyelination in mouse models of multiple sclerosis. The findings could have implications for treating multiple sclerosis in humans.
Researchers link the rise in acute stress and depression rates in the U.S to multiple stressors, such as unemployment and coronavirus-related media consumption.
Too much methionine in-vitro caused schizophrenia in mice, regardless of the level of postpartum care. Researchers suggest the same outcome would be true for humans.
