Gut microbes that metabolize tryptophan secrete indoles that stimulate the development of new neurons in the adult brain.
Researchers have uncovered the structure of psychedelic compounds when they actively bind to the 5-HT2A serotonin receptor on the surface of brain cells. The discovery could lead to the exploration of more precise compounds that offer the therapeutic effects of psychedelics for mental health disorders, but without the hallucinations.
Research examines the myths and science behind how the amino acid tryptophan, associated with turkey, affects mood.
A synthetic version of a fibupeptide, which is naturally produced by the microbiome, may help in the fight against antibiotic-resistant bacteria. Lugdunin has been shown to be effective against MRSA. The findings could help in the creation of a new class of antibiotics to treat infections currently resistant to drugs on the market.
Increased kynurenic acid production has been implicated in the pathology of schizophrenia. The findings provide a new target for cell-specific treatments that help reduce the production of kynurenic acid and reduce symptoms of schizophrenia.
A new study reveals a link between elevates microbiome levels of indole and hedonic eating. Researchers report those with higher levels of indole are more likely to have food addiction and overeating disorders.
Researchers examine the role gut bacteria plays in the development of neurological disorders. Using mouse models of multiple sclerosis, researchers found compounds generated from the breakdown of tryptophan can cross the blood-brain barrier and activate anti-inflammatory pathways that limit neurodegeneration. Activation of these pathway have also been linked to Alzheimer's and brain cancers.
A new study using piglets shows prebiotics used in baby formula can enhance memory and learning, as well as altering brain chemistry.
While research has cleared tryptophan of causing us to be sleepy following our Thanksgiving lunch, studies reveal TRP can promote interpersonal trust.