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          TRPML1

          This is a cartoon of an old couple
          FeaturedGeneticsNeuroscienceOpen Neuroscience Articles
          ·May 23, 2019·3 min read

          A new pathway for an anti-aging drug

          TRPML1 may contribute to the neuroprotective and anti-aging properties of rapamycin.
          Read More
          Image shows a the TRPML1 ion channel.
          FeaturedNeuroscience
          ·October 13, 2017·5 min read

          3D Atomic Structure of Ion Channel Implicated in Rare Neurodegenerative Disease

          Researchers from UT Southwestern's Cryo-EM Facility have determined the 3D anatomical structure of the TRPML1 ion channel. The ion channel has been implicated in mucolipidosis type IV, a rare, genetic neurodegenerative disease.
          Read More
          Image shows two mice.
          FeaturedGeneticsNeurology
          ·June 28, 2016·4 min read

          Possible New Therapy for a Rare Childhood Disease

          A new study reports bone marrow transplants can significantly delay the onset of motor deficits in mouse models of MLIV.
          Read More

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          A 3D digital rendering showing a developing fetal brain connected by glowing neural pathways and floating DNA strands, surrounded by subtle immune cells.

          How Severe Illness During Pregnancy Alters Fetal Brain Development

          A 3D digital illustration of a human brain side-by-side comparison, highlighting the language centers glowing brightly and equally in both a younger and older brain, while executive function areas are dimmed in the older brain.

          Aging Brains Maintain Robust Language Networks Despite Cognitive Decline

          Rejuvenation of Microglia by Youth Protein TIMP2 in the Aging Brain

          Youth Protein TIMP2 Restores Immune Function in the Aging Brain

          A multi-panel documentary photo. Left: A Black man sits alone on a locker room bench with his head down. Center: A Latino man sits withdrawn at a family kitchen table. Right: A White man looks thoughtfully at wellness pamphlets in a public waiting area. All convey isolation.

          Shame, Stigma, and Culture Prevent Male Domestic Violence Survivors From Seeking Help

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