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treatment resistant depression

·November 3, 2023·4 min read

New Gene Link to Treatment-Resistant Depression

Researchers discovered a gene, LHPP, that interacts with stress and plays a pivotal role in treatment-resistant Major Depressive Disorder (MDD) using an animal model. This groundbreaking study underscores the intricate dance between genetic risks and environmental factors in the onset of MDD.

Featured Neuroscience Psychology

·September 20, 2023·8 min read

Pioneering Biomarker for Resistant Depression Unearthed

Scientists have identified a unique biomarker in the brain that indicates recovery from treatment-resistant depression during deep brain stimulation (DBS). This significant discovery provides insights into DBS's effects on severe depression.

Featured Neuroscience Psychology

·December 14, 2022·5 min read

Patients With Treatment Resistant Depression at Higher Risk of Death

Study reveals people with treatment-resistant depression have a 23% higher risk of death than those without the condition.

Featured Neuroscience Psychology

·October 6, 2022·5 min read

Mechanism for the Antidepressant Effect of Ketamine Revealed

Those with treatment-resistant depression showed significant improvement in symptoms and became more receptive to positive experiences following a one-week ketamine treatment regimen.

This shows a brain and a finger shooting lightening out of it

Featured Neuroscience Open Neuroscience Articles Psychology

·November 22, 2021·8 min read

Novel Brain Stimulation Approach Treats Severe Depression

Combining deep-brain stimulation with intracranial EEG, researchers achieved an individualized understanding of specific brain networks that contributed to an individual's depression symptoms and identified stimulation patterns best suited to each patient for symptom relief.

This shows the researcher with the ECT machine

Featured Neuroscience Open Neuroscience Articles Psychology

·June 3, 2019·6 min read

Lower-amp ECT appears effective against suicidal thoughts

Low amplitude electroconvulsive therapy (ECT) lowers suicidal ideation in patients with major depressive disorder and bipolar depression, a new small randomized pilot study reveals. Within just three sessions, patients reported relief from suicidal thoughts.

image is a diagram of the dbs implants in the brain

Featured Neuroscience Psychology

·March 19, 2019·5 min read

Deep brain stimulation provides sustained relief for severe depression

Deep brain stimulation provides a significant reduction in the symptoms of depression for a number of patients with a treatment-resistant form of the disorder.

Featured Genetics Neuroscience Psychology

·August 17, 2018·5 min read

CRISPR Helps Target Mood Boosting Receptors in Brain

Researchers use CRISPR gene editing technology to target GABA receptors in order to help treat mood disorders.

Featured Neuroscience Psychology

·July 30, 2018·5 min read

Lack of a Single Molecule May Indicate Severe and Treatment Resistant Depression

A new study reports patients with major depressive disorder and treatment resistant depression have decreased levels of acetyl-L-carnitine in their blood. The findings could lead to new blood tests to diagnose the nature and severity of depression.

Featured Psychology

·June 30, 2018·5 min read

Amazonian Psychedelic May Ease Severe Depression

Ayahuasca, a psychedelic drink made from Amazonian plants, may help relieve symptoms in those with treatment resistant depression, researchers report.

Featured Neuroscience Open Neuroscience Articles Psychology

·January 26, 2018·5 min read

Magic Mushrooms May Alter How You Feel About Nature (and Politics)

Months after receiving psilocybin treatments for depression, patients report feeling more connected with nature and experience a shift away from authoritarian political views, researchers report.

Featured Neuroscience Open Neuroscience Articles Psychology

·January 15, 2018·8 min read

Can Psychedelic Drugs ‘Reconnect’ Depressed Patients with Their Emotions?

Two new studies consider the potential of using psychedelics to help treat depression. Imperial College London researchers report psilocybin, the active compound in magic mushrooms, can help to relieve symptoms of depression without the dulling of emotions associated with SSRIs. The researchers note the psychedelic experience could help to maintain long term mental health for those with treatment resistant depression.