A newly developed adeno-associated virus vector can deliver an anti-p Tau antibody directly to the hippocampus, significantly reducing pTau levels associated with CTE.
Male fruit flies fed a ketone supplemented diet expressed reduced levels of aggression following concussion than those who were not exposed to the dietary intervention.
Transplanting embryonic progenitor interneurons into the hippocampus of mouse models of TBI, researchers noticed the neurons migrated to the injury site and made new connections. Following treatment, memory improved and seizures were reduced.
Traumatic brain injury caused five times as many neurons in the amygdala to be active during white noise exposure in rats. Altered sensory processing within subcortical sensory-emotional networks following TBI impacts the facilitation of traumatic memory and may contribute to the development of PTSD.
MRI neuroimaging can distinguish between memory loss caused by Alzheimer's disease and traumatic brain injury. Using new image analysis software, researchers discovered TBI causes the most amount of damage to the ventral diencephalon, a brain area associated with memory and learning, and the least amount of atrophy to the hippocampus, a brain region most impacted by Alzheimer's.
21% of veterans who experience PTSD or traumatic brain injury suffer from a rare sleep condition that affects less than 1% of the general population. The condition, REM sleep behavior disorder (RBD), is characterized by an impairment of sleep-related muscle paralysis, causing people to act out dreams during REM sleep. The uncontrolled actions often cause harm to the sufferer of their partners.
A newly developed peptide hydrogel could help repair some of the damage caused by a traumatic brain injury. In rat models, the hydrogel improved the survival of brain cells, resulting in twice as many neurons at the injury site than in the control rats with TBI. Researchers reported new blood vessels also grew.
Microscopic alterations in white matter may affect how patients with neurological conditions respond to non-invasive electrical brain stimulation.
Side impact to the head can lead to rotational accelerations what cause mechanical vibrations to concentrate in the corpus callosum and periventricular region of the brain. Trauma to the side of the head can lead to concussions.
A new study identifies specific consumer products related to non-fatal brain injuries in children between the ages of 0 to 19. For infants, the leading cause of head injury is falling from beds, while in the teenage group, sporting equipment was the leading cause of TBI.
Over 50% of patients with mild traumatic brain injury reported their sense of smell was diminished following concussion. The effect does not appear to be long term.
Many survivors of domestic violence are likely to have experienced repeated head injuries and oxygen deprivation. The injuries resulted in memory loss, anxiety, and visual problems. Of the 49 people interviewed for this study, 81% report being hit in the head by their partner, while 83% report strangulation events.
