Anabolic androgenic steroids, drugs commonly associated with muscle building and enhancing athletic performance, are known to increase the risk for certain health disorders. A new study reveals anabolic steroids may also accelerate brain aging.
Lower levels of testosterone during puberty increases the brain's sensitivity to faces and expressions during adulthood.
Vitamin D deficiency during pregnancy may explain why males are three times more likely to be diagnosed with ASD than girls. The study reports prenatal vitamin d deficiency increases testosterone in the developing male brain.
Hard wired neural circuits in mice that govern aggression are strengthened following victories in aggressive encounters. Synapses in the hypothalamus show signs of LTP following aggression training.
A new study suggests COVID-19 may deplete testosterone levels in males. Findings reveal as testosterone decreased, the severity of coronavirus increased. Men who died from coronavirus infection had significantly lower mean testosterone than those who recovered. For those who were asymptomatic, 65.2% reported a loss in libido.
Researchers have uncovered specific regions of brain tissue where aromatase is present, that drives male sexual desire. Aromatase converts testosterone into estrogen in the brain, driving male sexual activity.
Males with autism have atypically enhanced excitation in the medial prefrontal cortex (mPFC). This area of the brain is associated with social cognition and self-reflection. Autistic women showed a more intact mPFC response, which was associated with a better ability to camouflage social difficulties in real-world settings.
Degarelix, a drug that reduces testosterone levels, shows potential in the treatment of pedophilic disorder. Men with a history of child sexual abuse who took the drug had reduced overall sexual desire and decreased attraction toward children, with noticeable effects within two weeks.
A circuit-specific gender difference in ventral hippocamps to nucleus accumbens (vHPC-NAc) neurons is dependent on testosterone and causes more susceptibility to stress in females.
A new study challenges the existing theory that testosterone levels are linked to reduced cognitive empathy.