TCF4

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TCF4

Autism Featured Genetics Neuroscience Open Neuroscience Articles

·May 2, 2022·5 min read

Gene Therapy Reverses Effects of Autism-Linked Mutation in Brain Organoids

A brain organoid study reveals how a genetic mutation associated with Pitt-Hopkins syndrome, a profound form of autism, disrupts neural development. Using gene-editing technology, researchers recovered the function of the TCF4 gene and effectively restored neural structure and function.

This shows a man breathing out a cloud of steam on a cold day

Autism Featured Neuroscience Open Neuroscience Articles

·October 13, 2021·4 min read

Rare Form of Autism Exhales Secrets of Breathing

Breathing difficulties associated with Pitt Hopkins syndrome, a rare form of autism, have been linked to a specific set of neurons in the brainstem.

Autism Featured Genetics Neuroscience

·February 3, 2020·4 min read

New study links autism to specific cell

Postmortem study reveals those with ASD have cellular abnormalities that impair the production of myelin.

Featured Genetics Neuroscience Open Neuroscience Articles Psychology

·September 14, 2019·4 min read

Scientists identify gene as master regulator in schizophrenia

TCF4 may serve as a master regulator of a gene network dysregulated in schizophrenia at the early stages of neurodevelopment.

Autism Featured Genetics

·March 11, 2016·4 min read

Study Identifies Potential Treatment for Autism Spectrum Disorder

Researchers have developed a potential treatment for Pitt-Hopkins syndrome, an autism spectrum disorder.

Featured Genetics Neuroscience

·August 9, 2012·5 min read

Neuroscientists Find Brain Stem Cells that May Be Responsible for Higher Functions, Bigger Brains

A neuron’s fate was thought to be determined by the timing of its birth date. Neuroscientists recently showed that there is a distinct stem cell progenitor that gives rise to upper layer neurons, regardless of birth date or place.

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