Using information generated by AI, researchers developed a novel anti-toxoplasmosis drug.
Behavioral changes in those with T.gondii infection could be linked to lower levels of norepinephrine. Norepinephrine also controls inflammation. Both neuroinflammation and norepinephrine are associated with a range of psychiatric disorders including schizophrenia and ADHD.
Microglia keep the Toxoplasma gondii parasite in check in the brain. Microglia release an immune molecule that recruit immune cells from the blood to control the parasite.
Mouse study reveals the sperm of males infected with Toxoplasma carries an altered epigenetic signature that impacts the brain of the offspring. While the effects of T. gondii infections in pregnant women are fairly well documented, this is a novel study looking at the impact of male infection and its impact on offspring. The study raises the question as to whether T. gondii infections in men before conception impact the health and development of future generations.
Study shows how Toxoplasma parasitic infections promote the loss of inhibitory signaling in the brain by altering the behavior of microglia.
Mice infected with the Toxoplasma gondii parasite showed no selective reduction in fear of feline predators. Findings reveal chronic T. gondii infection reduces anxiety and risk-aversion while increasing curiosity and exploratory behaviors.
A new, comprehensive database of gene activity in mice, which incorporates ten disease models, could significantly reduce the need for animal testing.
Immune system response to chronic infection may be more directly to blame for health and behavioral changes associated with Toxoplasma gondii infections.
Stockholm University researchers have discovered how a common parasite found in cat feces moves through the body and enters the brain. Toxoplasma gondii is able to take control of immune cells and use them to move through the body, eventually reaching the brain.
A new study in Scientific Reports reports T.gonfii infection may alter, or even amplify some neurological disorders including Alzheimer's and Parkinson's disease.
Study suggests new avenues for treating toxoplasmosis parasite infections.
A new study reports people with intermittent explosive disorder are twice as likely to have been exposed to toxoplasma gondii.
