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stem cells

Featured Genetics Neurology Open Neuroscience Articles

·September 15, 2021·3 min read

Stem Cells Model Genetic Risk for Developing Alzheimer’s Disease

Stem cell study reveals astrocytes carrying the Alzheimer's associated APOE4 gene release more cholesterol than those carrying the APOE3 gene. Findings shed light on how different versions of the APOE gene in astrocytes influence amyloid-beta production and how the oversupply of cholesterol associated with APOE4 astrocytes may promote amyloid-beta formation in Alzheimer's patients.

Featured Neurology Neuroscience

·September 1, 2021·5 min read

New Brain Model Provides Patient-Specific Alzheimer’s Insights and Predictions of Cognitive Decline

A newly developed brain model from cultivated stem cells allowed researchers to analyze molecular pathways of neurons in a dish. Researchers identified specific forms of amyloid beta and tau associated with cognitive decline and Alzheimer's. They also uncovered signaling pathways that influence the production of the toxic proteins.

Brain Cancer Featured Neurology Neuroscience Open Neuroscience Articles

·August 31, 2021·3 min read

Fighting Brain Cancer at Its Root

Researchers have identified specific proteins that drive the development of cancer stem cells. They report targeting and suppressing galectin1, in addition to radiation therapy, could be an effective treatment for glioblastoma brain cancer.

Featured Neuroscience

·August 23, 2021·6 min read

Brain Organoids With Complex Neural Activity Developed

Newly developed brain organoids grown from stem cells showed organized waves of neural activity similar to that seen in living human brains.

This shows amyloid beta in a staining sample

Featured Neurology Neuroscience

·August 7, 2021·3 min read

Miniature Brain Models Developed to Study the Causes of Alzheimer’s and Test Drugs in Development

Researchers have developed a new brain organoid model to study the mechanistic causes of Alzheimer's disease and test dementia drugs currently in development.

Featured Neurology Neuroscience

·July 26, 2021·5 min read

Early Signs of Frontotemporal Dementia Found in Personalized Cerebral Organoids

Researchers recreated the damage seen in frontotemporal dementia in brain organoid models. The study reveals an experimental drug designed to treat Crohn's disease may help prevent neuron death associated with FTD.

Featured Genetics Neurology Neuroscience Neuroscience Business

·June 23, 2021·3 min read

Cedars-Sinai Awarded $11.99 Million for ALS Clinical Trial

Cedars-Sinai has been awarded $11.99 million by California's stem cell agency to launch a clinical trial testing a potential gene and stem cell therapy for amyotrophic lateral sclerosis (ALS).

Brain Cancer Featured Neurology Neuroscience

·June 17, 2021·4 min read

Engineered Nk Cells Can Eliminate Glioblastoma Stem Cells

Engineering NK cells to resist immune suppression could be a path toward using NK cell-based immunotherapies for glioblastoma brain cancer.

Featured Genetics Neuroscience Open Neuroscience Articles

·May 25, 2021·4 min read

How to Boost Muscle Regeneration and Rebuild Tissue

Compounds used by researchers in stem cell research increase the regeneration of muscles in mice with age-related muscle loss.

This shows neural stem cells in the hippocampus

Featured Genetics Neuroscience

·February 27, 2021·3 min read

Reactivating Aging Stem Cells in the Brain

Increasing lamin B1 levels in aging mice resulted in neural stem cell division and an increase in the number of new neurons.

This shows a female scientist looking in a microscope

Featured Genetics Neuroscience

·February 22, 2021·4 min read

‘Mini Brain’ Organoids Grown in Lab Mature Much Like Infant Brains

Brain organoids, or mini-brains, created from human stem cells appear to develop in much the same way as a human brain. The organoids follow an internal clock that guides their maturation in sync with the timeline for human brain development.