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SPIE

·July 1, 2025·6 min read

Brain Stimulation Reverses Synaptic Damage in Alzheimer’s

New research shows that low-intensity repetitive transcranial magnetic stimulation (rTMS) can restore key synaptic structures in mouse models of Alzheimer’s disease. The study found that axonal boutons—sites where neurons form connections—had reduced turnover in Alzheimer’s mice, indicating impaired brain plasticity. After a single rTMS session, the turnover of one bouton type significantly increased, matching levels seen in healthy mice.

Featured Neuroscience

·June 4, 2024·4 min read

Brain Signals for Self-Timed Actions Revealed

Researchers explored how mice time their actions to receive rewards, focusing on the mesocortical brain pathway. The study found that dopamine-mediated signals via D2 receptors are crucial for self-initiated movements. These signals increase activity just before action but not in response to cues. The findings enhance our understanding of goal-directed behavior and its underlying brain mechanisms.

Featured Neuroscience

·January 8, 2024·6 min read

fNIRS Reveals New Insights Into Brain Activity

Researchers explore the potential of functional near-infrared spectroscopy (fNIRS) as a noninvasive tool to measure brain activity. Unlike invasive methods, fNIRS offers simplicity and portability, making it a promising option for real-world applications.

Featured Neuroscience

·April 26, 2023·6 min read

Unveiling the Hidden Biases in Medical AI: Paving the Way for Fairer and More Accurate Imaging Diagnoses

Researchers identified 29 sources of potential bias in artificial intelligence and machine learning (AI/ML) models used in medical imaging, ranging from data collection to model deployment. The report provides insights into the limitations of AI/ML in medical imaging and suggests possible ways for their mitigation, paving the way for a more equitable and just deployment of medical imaging AI/ML models in the future.