Researchers identified 11 areas of DNA that were linked to depression in women and one in males. They also found depression was associated with metabolic disease in women, providing an important new aspect to consider when treating depressive symptoms.
Exposure to drugs that target tauopathies extended survival, reduced neurodegenerative biomarkers, and functionally reduced aberrant behaviors in female mice, but not in males.
The anti-aging drug Rapamycin only prolongs the lifespan of females according to research using fruit fly and mouse models. Rapamycin increased autophagy in female intestinal cells, but not in males. Findings suggest biological sex may be a crucial factor in the effectiveness of anti-aging drugs.
Post-mortem analysis of the brains of those with Parkinson's disease revealed more than 200 genes with different epigenetic markers compared to healthy brains, but the affected genes were almost entirely different between women and men.
Researchers shed light on why the life expectancy and aging gap is narrowing between men and women.
The between-sex performance gap when it comes to running is much narrower at shorter sprint distances, a new study reveals.
Female mice show effects of the DAT mutation in brain regions unaffected in males, and vice versa. The findings reveal surprising differences in dopamine synapses between males and females controlling attention, pleasure, and motivation
Gene expression in male and female brains becomes more similar due to age, and both sexes contribute to the pattern. If the expression of a gene is higher in younger female brains it tends to be lower in younger male brains. Due to age, the gene expression reduces in females and increases in males, and vice versa.
Men who are happily married and have embarked upon higher education have a greater probability of outliving women. The findings challenge the conventional belief that most women outlive men.
Study reveals how reduced function of the rgs2 protein in the nucleus accumbens contributes to symptoms associated with depression. The findings may assist with the development of new therapeutics to help treat depression in individuals.
The COVID-19 pandemic and lockdowns affected girls' mental health more than boys', researchers report. Girls' emotional and behavioral difficulties increased by 1.6% compared to boys, and this was more pronounced in girls from lower socioeconomic backgrounds.
The sex of the drinker in addition to the brewing method may explain coffee's link to increased cholesterol. Drinking 3-5 cups of espresso per day increased serum total cholesterol, especially in males.