Alterations in the excitation and inhibition balance is regulated in the developing brain by astrocytes via the ephrin-B1 protein. The loss of astrocytic ephrin-B1 alters the E/I balance by reducing inhibition, resulting in hyperactivity of neural circuits. The hyperactivity results in reduced sociability in mice.
Study identifies a link between women with catamenial epilepsy who suffer more frequent seizures during their menstrual cycle and drug-resistant epilepsy. Those with catamenial epilepsy are almost four times more likely to have drug-resistant epilepsy than women who do not experience an increase in seizure frequency during their menstrual cycle.
8% of patients with a history of seizures reported experiencing hallucinations. Of the 8%, 53% reported one or more suicide attempts. Findings suggest hallucinations associated with seizures are not just incidental but are a marker for mental health risks and suicidal behavior.
Listening to Mozart's "Sonata for Two Pianos in D Major, K. 448" daily may reduce seizure activity for those with epilepsy.
Study shows how Toxoplasma parasitic infections promote the loss of inhibitory signaling in the brain by altering the behavior of microglia.
Findings shed light on what happens in the brains of patients with functional neurological disorders as well as other trauma-related brain disorders.
The neuropeptide NPY reduces seizures in human brain tissue.
Transplanting embryonic progenitor interneurons into the hippocampus of mouse models of TBI, researchers noticed the neurons migrated to the injury site and made new connections. Following treatment, memory improved and seizures were reduced.
A new study implicated interneurons and pyramidal cells in the ability of a seizure to spread through the brain.
A new study challenges the belief that epileptic seizures can be predicted by brain wave patterns. Researchers report they have found no evidence that specific brain wave patterns can be a predictive indicator of seizure onset.
CBD, which is a major phytocannabinoid constituent of cannabis, has already shown to have anti-epileptic, anti-anxiety, and anti-psychotic effects. The image is in the public domain.
Researchers say serotonin, a chemical commonly associated with mood regulation, may play in breathing problems associated with epileptic seizures. Those who had higher levels of serotonin following a seizure than before the event were less likely to experience interrupted breathing.