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          Sanford Burnham Prebys

          This shows a brain, DNA, and pills.
          FeaturedGeneticsNeurologyNeuroscience
          ·June 5, 2025·7 min read

          HIV Drugs Linked to Lower Alzheimer’s Risk

          FDA-approved HIV drugs targeting reverse transcriptase (RT) may reduce Alzheimer’s risk by blocking similar enzymatic activity in the aging brain. Scientists discovered unexpected RT activity in neurons of healthy and Alzheimer’s brains, tracing it to truncated LINE1 elements—ancient genetic sequences capable of copying themselves via RT.
          Read More
          This shows a person holding pills.
          FeaturedNeurologyNeuroscience
          ·April 16, 2024·5 min read

          HIV Drugs May Reduce Alzheimer’s Risk

          Common HIV drugs could reduce the incidence of Alzheimer’s disease (AD). Utilizing anonymized prescription data from over 225,000 individuals, the study found that HIV-positive patients taking reverse transcriptase (RT) inhibitors showed a significantly lower rate of AD compared to the general population.
          Read More
          This shows neurons.
          FeaturedNeurologyNeuroscience
          ·December 11, 2023·5 min read

          Astrocyte Study Ties Vitamin B12 to Multiple Sclerosis Progression

          A new study uncovers a molecular connection between vitamin B12 and multiple sclerosis (MS). The study identifies a key role of astrocytes and the brain's vitamin B12 carrier protein, transcobalamin 2, in this link.
          Read More
          This shows an eye
          FeaturedNeuroscienceVisual Neuroscience
          ·September 7, 2022·4 min read

          A Single Protein Could Unlock Age-Related Vision Loss

          Determining the structure of vitronectin, a protein implicated in age-related macular degeneration and some neurodegenerative disorders, and using pressure to alter the protein shape may help in the development of new treatments for AMD.
          Read More

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          This shows a brain.

          Genetic Roots of Depression Reveal Strong Suicide Risk Signals

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          Why Sharing Good Deeds Feels Bad

          This shows a brain and a gut.

          No Evidence the Gut Microbiome Causes Autism

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          Why Women Face Worse Long COVID

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