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SAD

This shows a woman sitting in a dark room.

·November 2, 2025·4 min read

Don’t Ignore the Winter Blues, It Could Be Seasonal Depression

As daylight fades, many experience fatigue or low mood—but for millions, these symptoms signal seasonal affective disorder (SAD), a serious form of depression. Reduced sunlight disrupts serotonin, melatonin, and the body’s circadian rhythm, leading to feelings of hopelessness, loss of interest, and sleep or appetite changes.

Featured Neuroscience Psychology

·November 12, 2022·3 min read

Ease Seasonal Affective Disorder With an Exercise Routine

Exercise can help improve mood and overall symptoms of those who suffer from seasonal affective disorder (SAD).

This is a diagram of how sunlight affects the SCN and helps control circadian rhythm

Featured Neuroscience Open Neuroscience Articles Psychology

·September 5, 2022·4 min read

How Changes in Length of Day Change the Brain and Subsequent Behavior

Neurons in the suprachiasmatic nucleus coordinate to adapt to different lengths of daylight, changing at cellular and network levels. The neurons changed in mix and expression of dopamine, altering brain activity and subsequently daily routine behaviors.

This shows a woman standing in the sunnshine

Featured Neuroscience Psychology

·July 7, 2022·5 min read

Brain Pathway That Helps to Explain Light’s Effect on Mood Discovered

Neuroimaging study reveals how light-sensitive signals reach the brain and how regions associated with mood process those signals. Some regions of the cerebral cortex associated with cognitive and mood processing show sensitivity to light intensity.

Featured Neuroscience Psychology

·February 4, 2022·3 min read

Beating Seasonal Affective Disorder

Seasonal affective disorder (SAD) impacts the lives of 5% of adults in the US. Researchers explore the best ways in which sufferers of SAD can improve their symptoms.

Featured Neuroscience Psychology

·February 23, 2021·4 min read

Seasonal Variation in Daylight Influences Brain Function

The seasonal duration of daylight influences the number of opioid receptors in the brain. The findings shed new light on a potential mechanism behind seasonal affective disorder.

This shows fish and the structure of NRF2

Featured Neuroscience Psychology

·April 13, 2020·2 min read

Discovery of a drug to rescue winter depression-like behavior

Fish model study found a potential target for the treatment of seasonal affective disorder (SAD). Researchers implicated NRF2 in seasonal depression and reported celastrol may help in the treatment of SAD.

This shows a sad looking woman sitting in a forest with bare trees and leaves on the ground

Featured Neuroscience Psychology

·November 2, 2019·4 min read

Seasonal Affective Disorder Impacts 10 Million Americans. Are You One of Them?

Seasonal affective disorder (SAD) affects over 10 million people in the US. Find out the symptoms and treatment options available.

Featured Neuroscience Psychology

·December 13, 2018·3 min read

‘Hangxiety’ Higher in Shy People

According to researchers, after a night of drinking, shy people are more likely to be anxious that those more extroverted.

Featured Psychology

·October 10, 2018·4 min read

Why Some Are More Prone To Depression Than Others

A new study reports people may be able to avoid depression, even if they have a genetic predisposition to SAD, by maintaining or boosting serotonin levels throughout the year.

Featured Neuroscience Open Neuroscience Articles

·April 24, 2018·3 min read

Brain Activity Linked to Stress Alters Chemical Codes

A new study identifies the mechanisms behind neurotransmitters involved in circadian changes. The study has implications for chemical imbalances in the brain that can lead to mental health problems.