In mice, natural melatonin is linked to a pre-hibernation state, allowing for a slower metabolism and survival when food is scarce or the temperature is too cold.
A mother's overwhelming desire to take risks in the face of danger to protect her child, and other nurturing behaviors, are driven by neurons in the cMPOA region of the hypothalamus which contains a protein called the calcitonin receptor.
Fenofibrate, a drug developed to control cholesterol, alleviated brain and behavioral abnormalities in mouse models of schizophrenia.
A specialized area of the mouse brain called the SuM specializes in detecting novel experiences. Within this brain area, responses to social novelty, or experiences related to unknown individuals, were segregated from those related to unfamiliar places, before being sent to areas of the brain associated with memory.
Specific combinations of microorganisms in the gut can worsen symptoms of multiple sclerosis in mouse models of the autoimmune disease.
Mouse study reveals slow-wave brain activity, which is indicative of sleep and resting states, is controlled by the claustrum. The synchronization of active and silent states across the brain via the slow waves contributes to consciousness.
People with schizophrenia have lower levels of S1P, a type of fatty molecule found in white matter. Evaluating post mortem tissue of those who died from a range of psychiatric disorders, researchers found the decreased levels of S1P in the brain was only attributed to those with schizophrenia. The findings could lead to new targeted treatments for the mental health disorder.
Neural stem cells affect the trajectory and timing of division in brain development more than previously believed. The findings provide insight into the mechanisms controlling early brain development and shed light on the evolution of the brain.