Abnormal neuron activity manifests as parental neglect
Abnormal activation of parvalbumin neurons in the young mouse auditory cortex manifests as a result of maternal neglect.... Read More...
Rett Syndrome
Pupil dilation and heart rate, analyzed by AI, may help spot autism early
A machine learning algorithm can accurately detect abnormalities in pupil dilation, which are predictive of ASD, in mouse models. The AI can also detect if a female has Rett syndrome with 80% accuracy. The system could be used to detect autism in infants and toddlers.... Read More...
Discovery of the Genetics Conductor of Brain Stem Cells
Researchers describe their findings about how the Foxg1 gene is involved in the development and differentiation of neurons and glial cells from stem cells.... Read More...
Genetic Mechanism Involved in How Females Inherit Traits Identified
Researchers have identified a specific mechanism involved in how females inherit traits. The findings could help reduce susceptibility to Fragile X and Rett syndrome, the researchers report.... Read More...
Researchers Reverse Symptoms in Rett Syndrome Model
Activating neurons in the medial prefrontal cortex can reverse breathing and memory abnormalities in mouse models of Rett syndrome, researchers report.... Read More...
X Chromosome Reactivation Could Treat Rett Syndrome and Other X-Linked Disorders
Mass General researchers have developed a strategy for treating disorders related to the X chromosome.... Read More...
Gene Regulation in Brain May Explain Repetitive Behaviors in Rett Syndrome Patients
A new study reports a protein associated with Rett syndrome is also among a group of three proteins that affect the function of a gene previously linked to OCD.... Read More...
Brain’s Stunning Genomic Diversity Revealed
Researchers report on how jumping genes can go awry and cause disease.... Read More...
Cancer and Autism Share a Remarkable Number of Risk Genes in Common
Researchers have identified more than 40 common genes in cancer and autism disorders.... Read More...
Researchers Identify a Possible New Drug Target for Rett Syndrome
Researchers have identified an important signaling pathway that, when corrected, appears to improve symptoms of Rett syndrome in mice.... Read More...
New Drug Target May Lead to Novel Treatment for Severe Autism
Findings could lead to new treatments for Rett Syndrome and other forms of autism, researchers report.... Read More...
Stem Cell Derived ‘Mini Brains’ Reveal Potential Drug Treatment for Rare Disease
Researchers have identified a drug candidate which appears to suppress a critical genetic alteration in dysfunctional cells.... Read More...