Piezo1 limits the potential of regulatory T cells (Treg) to mitigate autoimmune neuroinflammation. Inhibiting Piezo1 could lead to new treatments for autoimmune disorders like multiple sclerosis.
Combining αGITR antibodies with ICBs resulted in stronger survival benefits in mouse models of human glioblastoma brain cancer.
A groundbreaking new study reveals an unexpected interaction between men's testes and the immune system. Additionally, the findings could help explain the development of certain autoimmune disorders and why some cancer vaccines are ineffective.