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reelin

·October 8, 2025·5 min read

Reelin Shows Promise for Healing Both Gut and Depression

A new study reveals that the protein Reelin may hold the key to treating both “leaky gut” and major depressive disorder. Chronic stress lowers Reelin levels in the gut, weakening the intestinal barrier and allowing toxins to trigger inflammation that worsens depression.

Featured Neurology Neuroscience

·July 24, 2024·9 min read

Neural Vulnerabilities and Resilience in Alzheimer’s Explored

Researchers uncover how specific brain cells and circuits become vulnerable in Alzheimer's disease and identify factors that may promote resilience to cognitive decline. Analyzing gene expression in over 1.3 million cells across multiple brain regions, the study highlights the role of Reelin in neuron protection and choline metabolism in astrocytes for cognitive resilience. These findings pave the way for potential therapeutic targets to sustain cognition and memory amid Alzheimer’s pathology.

Featured Genetics Neurology

·August 12, 2020·4 min read

‘Reelin’ in a New Treatment for Multiple Sclerosis

Decreasing the amount of Reelin significantly protected against disease symptoms and promoted recovery in symptomatic animal models of multiple sclerosis. Reelin levels appear to correlate with MS severity and stages. Researchers report lowering levels of the protein could be a potential avenue of treatment for the autoimmune disorder.