Acute inflammation of the anterior cerebellum resulted in depression-like symptoms in rodent models. Suppressing microglia helped reduce hyperexcitability and symptoms of depression. Read More
In mice genetically engineered to carry human stuttering mutations, vocalization defects are derived from abnormalities in astrocytes in the corpus callosum. Read More
Mouse study reveals neonatal nicotine exposure primes the ventral tegmental area, making the animals more susceptible to the effects of nicotine when exposed again later in life. Read More
Findings provide evidence to support the role of human roseoloviruses, HHV-6A, and HHV-6B in bipolar disorder and major depressive disorder. Read More
Researchers discover higher infection rates in Purkinje cells with the herpesvirus HHV-6 in patients with bipolar disorder. Read More
Computational neurosciences have created a virtual version of Purkinje cells in the brain's cerebellum. The virtual cells may shed light on how Purkinje cells work. Read More
Researchers report the ANKRD16 can prevent protein aggregates associated with neurodegenerative diseases. Read More
A new study sheds light on how the cerebellum is able to make predictions and learn from mistakes, especially when it comes to completing complex motor actions. The findings could help in the development of new machine learning technologies. Read More
Gene expressions in the brain that occur early in development may explain why some cerebellar stem cell populations behave differently in people with SCA1, researchers report. Read More
Researchers report molecular networks on both sides of a synapse are important for controlling learning. Read More
Researchers have derived purkinje cells from patients with TSC, a genetic syndrome that includes some ASD-like symptoms. The cells, researchers say, have several characteristics that could help explain how ASD develops at the molecular level. Read More
Researchers shed light on the role Synaptotagmin 7 plays in neurotransmission in inhibitory synapses. Read More