FeaturedNeuroscience·June 16, 2022·3 min readResearchers Described How the Cerebellum Modulates Our Ability to SocializeDopamine in the cerebellum helps regulate social behaviors via its action on D2 receptors. Changes in D2 levels in Purkinje cells alter sociability and preference for social novelty without affecting motor function.Read More
ElectrophysiologyFeaturedNeuroscienceOpen Neuroscience Articles·July 10, 2021·4 min readCell Structure Previously Associated With Disease Actually Improves Brain FunctionAxonal swelling in the Purkinje cells of mice had no detrimental impact on firing rate or the speed at which axons transmit signals. At peak firing rate, axons with swellings were less likely to fail than those without.Read More
FeaturedNeuroscience·March 11, 2021·5 min readGrowing Neurons Gain an Edge by Making ConnectionsFindings shed new light on how the brain wires during development.Read More
FeaturedNeuroscienceOpen Neuroscience ArticlesPsychology·September 13, 2019·3 min readAcute cerebellar inflammation and hyperexcitability induces ‘depression-like’ behaviorAcute inflammation of the anterior cerebellum resulted in depression-like symptoms in rodent models. Suppressing microglia helped reduce hyperexcitability and symptoms of depression.Read More
FeaturedNeuroscience·August 19, 2019·6 min readStudy identifies type of brain cell involved in stutteringIn mice genetically engineered to carry human stuttering mutations, vocalization defects are derived from abnormalities in astrocytes in the corpus callosum.Read More
FeaturedNeuroscience·May 22, 2019·4 min readEarly life exposure to nicotine alters neurons, predisposes brain to addiction laterMouse study reveals neonatal nicotine exposure primes the ventral tegmental area, making the animals more susceptible to the effects of nicotine when exposed again later in life.Read More
FeaturedGeneticsNeuroscienceOpen Neuroscience ArticlesPsychology·April 7, 2019·3 min readHerpes virus link to bipolar disorder and depressionFindings provide evidence to support the role of human roseoloviruses, HHV-6A, and HHV-6B in bipolar disorder and major depressive disorder.Read More
FeaturedNeurosciencePsychology·August 10, 2018·3 min readSurprise Finding in NeuronsResearchers discover higher infection rates in Purkinje cells with the herpesvirus HHV-6 in patients with bipolar disorder.Read More
FeaturedNeuroscienceOpen Neuroscience Articles·August 7, 2018·5 min readUpgrade for Virtual Brain CellComputational neurosciences have created a virtual version of Purkinje cells in the brain's cerebellum. The virtual cells may shed light on how Purkinje cells work.Read More
FeaturedGeneticsNeurology·May 16, 2018·3 min readGene that Helps Prevent Brain Disease IdentifiedResearchers report the ANKRD16 can prevent protein aggregates associated with neurodegenerative diseases.Read More
FeaturedNeuroscience·May 3, 2018·7 min readDecoding the Brain’s Learning MachineA new study sheds light on how the cerebellum is able to make predictions and learn from mistakes, especially when it comes to completing complex motor actions. The findings could help in the development of new machine learning technologies.Read More
FeaturedGeneticsNeurology·March 30, 2018·4 min readAdult Onset Neurodegeneration Has Roots in Early DevelopmentGene expressions in the brain that occur early in development may explain why some cerebellar stem cell populations behave differently in people with SCA1, researchers report.Read More
