Latest

PSP

·July 22, 2025·6 min read

Synaptic Tau and Astrocytes Drive PSP Progression

ew research uncovers how tau pathology spreads and damages synapses in progressive supranuclear palsy (PSP). Using human postmortem tissue and live brain slice models, scientists showed tau accumulates in both pre- and postsynaptic terminals, likely propagating neuron-to-neuron.

Featured Neurology Neuroscience

·April 30, 2025·5 min read

Skin Test Detects Neurodegenerative Disease PSP with High Accuracy

Researchers have developed a skin-based test that can detect misfolded tau proteins specific to progressive supranuclear palsy (PSP), offering a faster, more accurate diagnosis than current methods. This breakthrough could improve patient assignment to clinical trials and eventually guide targeted, precision treatments.

Featured Neurology Neuroscience

·September 4, 2024·4 min read

Drug Trial Offers Hope for Progressive Supranuclear Palsy

A new clinical trial will test three drugs concurrently to find treatments for progressive supranuclear palsy (PSP), a rare and fatal neurodegenerative disorder. The trial aims to slow the relentless progression of PSP, which currently has no cure.

Featured Neurology Neuroscience

·July 5, 2024·6 min read

Breakthrough in Diagnosing Deadly Brain Disorder PSP

Researchers identified protein biomarkers in spinal fluid that can diagnose progressive supranuclear palsy (PSP) in living patients. Using high-throughput technology, they found a distinct protein pattern in PSP patients, offering hope for early diagnosis and targeted treatments.

Featured Genetics Neurology Neuroscience

·November 3, 2023·5 min read

Promising Targets Discovered for Rare Brain Disorder PSP

Researchers have identified new therapeutic targets for progressive supranuclear palsy (PSP), an incurable brain disorder with symptoms mimicking Parkinson's and dementia. The study focused on RNA sequencing from brain samples of over 400 individuals.

Featured Neurology Neuroscience

·January 6, 2023·4 min read

Inflammatory Trigger a New Clue in Alzheimer’s and PSP

An inflammatory trigger like one present during viral infections is elevated in those with Alzheimer's disease and progressive supranuclear palsy (PSP).

Featured Neurology Neuroscience

·October 13, 2022·5 min read

Memory and Logic Test Detects Dementia Signs up to Nine Years Ahead of Diagnosis

People who later developed Alzheimer's disease scored poorly on memory and logic-based tests, as well as reaction times and grip tests. They were also more likely to have experienced a fall within the past 12 months. Those who developed PSP were twice as likely to experience a fall.

Featured Genetics Neurology Neuroscience

·August 18, 2022·6 min read

New Dementia Risk Genes Identified Through Novel Testing Approach

Researchers have identified multiple new risk genes for Alzheimer's disease and progressive supranuclear palsy (PSP).

Featured Neurology Neuroscience

·April 21, 2022·4 min read

Novel Deep Learning Method Provides Early and Accurate Differential Diagnosis for Parkinsonian Diseases

A new deep learning algorithm utilizes neuroimaging data to differentiate between Parkinson's disease and other parkinsonian syndromes such as PSP and multiple systems atrophy.

This shows different drawings of neurons from healthy to diseased

Featured Neurology Neuroscience Open Neuroscience Articles

·April 19, 2022·4 min read

Research Team Affirms Useful Blood Biomarker for Group of Brain Disorders in New Study

Study confirms neurofilament light is a useful blood-based biomarker for frontotemporal dementia, PSP, and primary progressive aphasia.

Featured Neurology Neuroscience

·April 7, 2022·4 min read

Brainstem Atrophy Is Linked to Extrapyramidal Symptoms in Frontotemporal Dementia

Patients who suffer from frontotemporal dementia with extrapyramidal symptoms have brainstem atrophy and reduced metabolic activity in specific brain regions compared to those with FTD without extrapyramidal symptoms.

Featured Neurology Neuroscience

·April 4, 2022·7 min read

Loss of Neurons, Not Lack of Sleep, Makes Alzheimer’s Patients Drowsy

Degeneration of neurons associated with wakefulness, and not a lack of sleep, makes Alzheimer's patients more drowsy. The degeneration of these neurons is caused by the tau protein. In PSP, the damage to the neurons was associated with symptoms of sleep deprivation.

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PSP

Synaptic Tau and Astrocytes Drive PSP Progression

Skin Test Detects Neurodegenerative Disease PSP with High Accuracy

Drug Trial Offers Hope for Progressive Supranuclear Palsy

Breakthrough in Diagnosing Deadly Brain Disorder PSP

Promising Targets Discovered for Rare Brain Disorder PSP

Inflammatory Trigger a New Clue in Alzheimer’s and PSP

Memory and Logic Test Detects Dementia Signs up to Nine Years Ahead of Diagnosis

New Dementia Risk Genes Identified Through Novel Testing Approach

Novel Deep Learning Method Provides Early and Accurate Differential Diagnosis for Parkinsonian Diseases

Research Team Affirms Useful Blood Biomarker for Group of Brain Disorders in New Study

Brainstem Atrophy Is Linked to Extrapyramidal Symptoms in Frontotemporal Dementia

Loss of Neurons, Not Lack of Sleep, Makes Alzheimer’s Patients Drowsy

What Triggers Tantrums? Sensory Overload May Be To Blame

Brain Circuit That Forces Behavior Into “Repeat Mode” Identified

Genetics Plus Heart Health Markers Sharpen Dementia Risk

Supplement Shows Promise in Blocking Amyloid in Alzheimer’s

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