Stimulating noradrenergic neurons in the locus coeruleus that carry signals from the brain down the spinal dorsal horn activates astrocytes. The astrocyte activation results in hypersensitivity to pain. Read More
A study of four drugs to combat chronic neuropathic pain finds Nortriptyline has the highest efficacious percentage and lowest quit rate. Read More
SARS-CoV-2, the virus responsible for COVID-19 suppresses pain. Findings suggest the pain suppression caused by the infection may be responsible for viral spread, as people do not feel as ill as they actually are. Read More
Skin-to-skin contact between a parent and newborn reduces how strongly a baby's brain responds to pain. Read More
Middle-ages adults are reporting more chronic pain symptoms than older generations. Those who are less educated are more likely to report symptoms of chronic pain. Read More
An extract of turmeric is more effective than a placebo at reducing pain in those with knee osteoarthritis. Following 12 weeks of exposure to the extract, people reported less pain than those taking a placebo. Read More
Unlike long-term opioid use, frequent cannabis use does not increase sensitivity to pain. Read More
People with osteoarthritis in the knee who report more pain sensations are more likely to suffer constant and unpredictable pain. Researchers identified a potential mechanism in the nervous system that could explain why people experience varying pain patterns associated with knee osteoarthritis. Read More
Researchers explore the close relationship between depression and pain. For some people, unexplained symptoms of pain, such as back or headaches, could be an early indicator of depression before mood changes occur. Read More
c-Fos accumulates in the nucleus of peripheral nerve cells of mouse models of chronic pain. Researchers identified around 30 existing drugs that appear to target the importin alpha-3-c-Fos pathway to help treat chronic pain. Read More
Genomic research finds those who inherited a special ion channel from Neanderthals experience more pain. Read More
