Researchers end decade-long search for mechanical pain sensor
Researchers have that discovered a protein in the membrane of sensory neurons is involved in our capacity to experience mechanical pain.... Read More...
pain
Acetaminophen and forgiveness may alleviate emotional and physical pain of exclusion
For those who face social rejection, researchers believe they have found a simple antidote. The study reports combining the over-the-counter pain killer acetaminophen with a dose of forgiveness can help alleviate both the physical and emotional pain of social rejection.... Read More...
Casting light on the brain’s inner workings
Neuroengineers have created an ultra-small, wireless, battery-free device that uses light to record individual neurons. The device will give researchers a new platform to gain insight into the underpinning mechanisms of the brain.... Read More...
First treatment for pain using human stem cells a success
Transplanting GABAergic cells derived from human-induced pluripotent stem cells into mice resulted in safe, lasting, and effective relief from extreme neuropathic pain. Researchers hope to begin human testing within five years.... Read More...
Nerve stimulation may benefit women with fibromyalgia
TENS nerve stimulation resulted in significant improvements in movement-related pain and fatigue in women who suffer from fibromyalgia.... Read More...
Early prevention of neuropathic pain
Intercepting CCL2 with specific antibodies may provide an early intervention for chronic neuropathic pain.... Read More...
How the brain balances pleasure and pain
Different classes of neurons in the ventral pallidum control positive and negative motivations, sending opposing signals along a shared motivation-processing circuit.... Read More...
Battery-powered headgear could short-circuit joint pain
A portable transcranial direct current stimulation headset may provide relief for those with joint pain.... Read More...
One in three pain patients suffer side effects after ketamine infusion therapy
35% of patients who used ketamine to manage pain reported significant side effects ranging from hallucination, out-of-body experiences, visual disturbances, and urinary dysfunction. 20% of the side effects were linked directly to ketamine, and 15% associated with ketamine in combination with other drugs.... Read More...
Brain mechanisms have potential to block arthritis pain
Researchers discover the amygdala is a critical site of action for pain modulation. An existing compound, LY379268, provides pain-relieving effects and helps to reduce anxiety.... Read More...
Molecular link between chronic pain and depression revealed
Inhibitory inputs to the neural circuit between the dorsolateral bed nucleus of the stria terminalis (dlBNST) to the ventral tegmental area (VTA) increase when a person is in chronic pain. This alteration is mediated by enhanced corticotropin-releasing factor signaling within the dlBNST, leading to suppression of the mesolimbic dopaminergic system. The result is depressive mood and anhedonia associated with chronic pain.... Read More...
Persistent headache or back pain ‘twice as likely’ in the presence of the other
Researchers have identified a positive association between persistent lower back pain and headache disorders. The study reveals those with persistent back pain or persistent headache disorders are twice as likely to suffer from both disorders at the same time.... Read More...