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pain

·June 30, 2026·11 min read

Does Melatonin Help Reduce Chronic Pain?

Melatonin can reduce chronic musculoskeletal pain by 9 to 10 points on a 100-point scale. This therapeutic relief matches the efficacy of opioids and NSAIDs while bypassing their severe risks of organ toxicity and addiction, offering a safe, non-dependent adjunct that treats pain and sleep disruption simultaneously.

Featured Genetics Neurology Neuroscience Pain

·June 1, 2026·8 min read

HIV Protein gp120 Directly Amplifies Spinal Pain Receptors

A new study isolates the exact molecular mechanisms by which the viral protein glycoprotein 120 (gp120) intensifies neuropathic suffering.

Featured Neurology Neuroscience

·June 1, 2026·9 min read

AI System Successfully Decodes and Tracks Pain via EEG

A new study introduces an artificial intelligence framework that analyzes EEG signals to objectively classify pain intensity.

Featured Genetics Neuroscience

·June 1, 2026·6 min read

Stem Cell Particles Target and Reset Chronic Nerve Pain

A new project is investigating whether tiny stem-cell-derived particles can treat intractable neuropathic pain.

Featured Neurology Neuroscience Pain

·May 26, 2026·8 min read

Brain Pathway Identified That Amplifies Nocebo Pain Responses

Summary: Researchers mapped the precise brain pathway that drives the nocebo effect, the biological phenomenon where negative expectations actively amplify...

Featured Neurology Neuroscience Pain

·May 22, 2026·8 min read

Psilocybin Resets Brain Pain Networks and Boosts Painkillers

A single dose of psilocybin provides up to a month of nerve pain relief and fundamentally supercharges the efficacy of traditional painkillers.

Featured Neurology Neuroscience Pain

·May 19, 2026·11 min read

Tracking Facial Micromovements to Measure Pain

A new study demonstrates that tracking high-speed facial micromovement spikes provides an objective, quantifiable metric for human discomfort.

This shows an older woman surrounded by leaves.

Featured Neuroscience Pain Psychology

·May 8, 2026·9 min read

The “Goldilocks” Choice: Why Older Adults are Turning to Cannabis

New research shows that seniors are turning to edible cannabis to manage pain and sleep, often choosing "Goldilocks" combination products based on advice from friends rather than doctors.

Featured Neuroscience Pain

·April 23, 2026·7 min read

25% of Chronic Pain Patients Show ADHD Traits

A study of 1,000 Japanese patients reveals that undiagnosed ADHD traits may be a hidden driver behind treatment-resistant chronic pain.

Featured Neurology Neuroscience Pain

·April 16, 2026·8 min read

The Brain Circuitry of Placebo Pain Relief

Researchers have pinpointed the brain's "placebo circuit." By training the brain to release its own endorphins in the vlPAG region, they achieved broad-spectrum pain relief without the need for addictive drugs.

Featured Neurology Neuroscience Pain

·April 2, 2026·9 min read

Brain Circuit That “Invents” Chronic Pain Identified

Neuroscientists have identified a dedicated brain circuit responsible for chronic pain. By silencing this loop, researchers were able to end pain hypersensitivity in mice without affecting their ability to feel necessary, acute pain.

Featured Neurology Neuroscience Pain

·April 1, 2026·9 min read

High-Potency Opioid Relieves Pain Without the Risks

Researchers have engineered a novel nitazene-based opioid, DFNZ, that provides potent pain relief without causing respiratory depression or addiction. The "superagonist" drug could revolutionize treatment for chronic pain and opioid use disorder.

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pain

Does Melatonin Help Reduce Chronic Pain?

HIV Protein gp120 Directly Amplifies Spinal Pain Receptors

AI System Successfully Decodes and Tracks Pain via EEG

Stem Cell Particles Target and Reset Chronic Nerve Pain

Brain Pathway Identified That Amplifies Nocebo Pain Responses

Psilocybin Resets Brain Pain Networks and Boosts Painkillers

Tracking Facial Micromovements to Measure Pain

The “Goldilocks” Choice: Why Older Adults are Turning to Cannabis

25% of Chronic Pain Patients Show ADHD Traits

The Brain Circuitry of Placebo Pain Relief

Brain Circuit That “Invents” Chronic Pain Identified

High-Potency Opioid Relieves Pain Without the Risks

Gene Therapy Reverses Severe Traits of Fragile X Syndrome

Loneliness Directly Causes Poor Mental Health

Aligning Brain Waves and Machine Learning

Blood Test Accurately Predicts Five-Year Alzheimer’s Risk

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