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          p11

          This shows a stressed man
          FeaturedNeuroscienceOpen Neuroscience ArticlesPsychology
          ·October 2, 2020·4 min read

          New Clues About the Link Between Stress and Depression

          p11, a protein implicated in serotonin function, affects the initial release of cortisol in mice by modulating the activity of specific neurons in the hypothalamus. Previous studies found people with depression lave lower levels of p11 in their brains. The findings could help in the development of new treatments for depression and stress.
          Read More
          Image shows how p11 increases mGluR5.
          FeaturedPsychology
          ·September 30, 2015·4 min read

          Gaining Insight Into How a New Class of Antidepressants Work

          Researchers explain how a molecular amplification system helps a new class of antidepressants alter brain signaling in specific neurons and how this produces the antidepressant effect.
          Read More
          This image shows midbrain mouse neurons.
          FeaturedGeneticsNeuroscience
          ·May 23, 2014·3 min read

          Researchers Profile Active Genes in Neurons Based on Connections

          Researchers have devised a way to create snapshots of gene expression in neurons based on their connections.
          Read More

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          A 3D digital rendering showing a developing fetal brain connected by glowing neural pathways and floating DNA strands, surrounded by subtle immune cells.

          How Severe Illness During Pregnancy Alters Fetal Brain Development

          A 3D digital illustration of a human brain side-by-side comparison, highlighting the language centers glowing brightly and equally in both a younger and older brain, while executive function areas are dimmed in the older brain.

          Aging Brains Maintain Robust Language Networks Despite Cognitive Decline

          Rejuvenation of Microglia by Youth Protein TIMP2 in the Aging Brain

          Youth Protein TIMP2 Restores Immune Function in the Aging Brain

          A multi-panel documentary photo. Left: A Black man sits alone on a locker room bench with his head down. Center: A Latino man sits withdrawn at a family kitchen table. Right: A White man looks thoughtfully at wellness pamphlets in a public waiting area. All convey isolation.

          Shame, Stigma, and Culture Prevent Male Domestic Violence Survivors From Seeking Help

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