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oncology

·August 18, 2020·4 min read

Drugs Against Alpha-Ketoglutarate May Combat Deadly Childhood Brain Tumor

Experimental drugs designed to reduce the body's natural production of alpha-ketoglutarate slow tumor growth and increase lifespan in mouse models of DIPG.

The image shows a microscopic view of a typical neuroblastoma with rosette formation.

Brain Cancer Featured

·January 29, 2013·2 min read

Dendritic Cell Vaccine for Relapsed Neuroblastoma Patient Induces Complete Remission

Cancer treatment vaccine research leads to remission in a child with a relapsed neuroblastoma.

Neurons are shown. Caption describes it well.

Brain Cancer Featured Neurology

·October 22, 2012·3 min read

Aggressive Brain Tumors Can Originate from a Range of Nervous System Cells

Scientists have long believed that glioblastoma multiforme, the most aggressive type of primary brain tumor, begins in glial cells that make up supportive tissue in the brain or in neural stem cells. Researchers found that the tumors can originate from other types of differentiated cells in the nervous system, including cortical neurons.

Brain Cancer Featured Genetics Neurology

·September 4, 2012·3 min read

New Gene Variants Found to Raise Risk of Neuroblastoma and Influence Tumor Progression

Researchers have discovered two gene variants that raise the risk of the pediatric cancer neuroblastoma. This is the first study to link known cancer-related genes HACE1 and LIN28B to neuroblastoma. The study broadens understanding of how gene changes may make a child susceptible to this early childhood cancer, as well as causing a tumor to progress.

Brain Cancer Featured Neurology

·August 24, 2012·3 min read

Survival Statistics Show Hard Fight When Malignant Brain Tumors Appear at Multiple Sites

When aggressive, malignant tumors appear in more than one location in the brain, patient survival tends to be significantly shorter than when the disease starts as a single tumor, even though patients in both groups undergo virtually identical treatments, according to research at Cedars-Sinai Medical Center's Maxine Dunitz Neurosurgical Research Institute.