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Nrf2

·May 23, 2022·3 min read

New Research May Explain Unexpected Effects of Common Painkillers

Researchers uncover the mechanism behind how a subset of NSAIDs reduces inflammation, which helps explain some of the curious side effects of the anti-inflammatories.

Featured Neurology Neuroscience

·February 1, 2022·4 min read

Compound in the Herb Rosemary May Be Useful Against COVID-19 and Other Inflammatory Diseases

Carnosic acid, a compound found in the herb rosemary, can block the interaction with the COVID-19 SARS_CoV_2 spike protein and ACE2, the protein receptor the virus uses to gain access into cells. The compound appears to have anti-inflammatory effects and has previously been associated with a reduction in Alzheimer's symptoms.

Featured Neurology Neuroscience

·October 25, 2021·4 min read

Deterioration of Brain Cells in Parkinson’s Disease Is Slowed by Blocking the Bach1 Protein

Bach1, a protein that blocks the expression of genes associated with neuroprotection, has been implicated in Parkison's disease. Researchers say blocking Bach1 slows the deterioration of brain cells in preclinical models of Parkinson's disease.

Brain Cancer Featured Genetics Neurology Neuroscience

·December 8, 2020·4 min read

Reductive Stress in Neuroblastoma Cells Aggregates Protein and Impairs Neurogenesis

Reductive stress promotes protein aggregation in neuroblastoma cells and impairs neurogenesis.

This shows fish and the structure of NRF2

Featured Neuroscience Psychology

·April 13, 2020·2 min read

Discovery of a drug to rescue winter depression-like behavior

Fish model study found a potential target for the treatment of seasonal affective disorder (SAD). Researchers implicated NRF2 in seasonal depression and reported celastrol may help in the treatment of SAD.

Featured Genetics Neuroscience Open Neuroscience Articles

·January 12, 2019·4 min read

Metabolite Produced By Gut Bacteria From Pomegranates Reduces IBD

Researchers report UroA, a microbial metabolite derived from a compound found in pomegranates and berries, can reduce and protect against inflammatory bowel disease.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·August 21, 2018·4 min read

How the Body Clock Controls Inflammation

A new study sheds light on how the circadian clock controls inflammatory response. By understanding the link between inflammation and circadian rhythm, researchers believe it may be most effective to target specific conditions at certain times of the day. The findings may also explain why those who experience body clock disruptions are more susceptible to inflammatory conditions.

Featured Genetics Neurology

·December 26, 2016·4 min read

Single Protein May Hold Secret to Treating Parkinson’s

Activating Nrf2 helps with the removal of LRRK2 and alpha synuclein, researchers report.

Featured Neurology

·June 8, 2016·7 min read

Metabolite of MS Drug May Be Safe and Effective Parkinson’s Treatment

A drug usually used for the treatment of multiple sclerosis appears to increase the activity of Nrf2, a protein that protects the body from oxidative stress and inflammation associated with Parkinson's disease.