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NMR

Image shows a 3-D reconstruction of an amyloid fibril

·September 8, 2017·6 min read

Sharpest Image of Alzheimer’s Fibrils Shows Previously Unknown Details

Researchers have captured some of the sharpest images of Alzheimer's associated amyloid fibrils to date. The 3D structure of the fibrils displays some previously unknown structural details that researchers believe could help answer some important questions about the development of Alzheimer's disease.

Image shows an artist wooden model standing with a shadow that is slumped over.

Featured Open Neuroscience Articles Psychology

·July 27, 2016·5 min read

New Model May Solve Mystery of How Lithium Stabilizes Mood

Findings could help to design new treatments for mood disorders as effective as lithium, but with fewer side effects.

Image of Alpha-Synuclein Fibril Structure.

Featured Neurology Neuroscience Videos

·March 29, 2016·4 min read

Structure of Parkinson’s Protein May Lead to New Treatment and Diagnostic Options

Researchers have identified the complex chemical structure of alpha-synuclein.

Featured Neurology

·March 1, 2016·3 min read

The Evolution of Amyloid Toxicity in Alzheimer’s

Researchers have uncovered structural markers to differentiate between smaller and larger forms of amyloid beta molecules.

Illustration of structure of enzyme catalase.

Featured Genetics

·October 9, 2015·5 min read

Finding New Clues About How Proteins Fold

A new technique allows researchers to analyze the structure a protein forms as it interacts with other proteins in a cell.

This image shows an NMR scan of a human head.

Featured Genetics Open Neuroscience Articles

·July 8, 2015·4 min read

Hope for Patients With Leukodystrophies

Researchers have identified a new gene associated with 4H leukodystrophy.

Featured Neuroscience

·June 24, 2013·4 min read

NMR Advance Brings Proteins into the Open

Researchers combine data from four different NMR techniques to observe chaperone GroEL capture a disordered beta-amyloid protein.

Electrophysiology Featured Neuroscience

·July 12, 2012·10 min read

Large, Medically Important Class of Proteins Starts to Yield Its Secrets

Five recent research papers shed light on elusive G protein-coupled receptors. New techniques and insights used to solve the GPCR structures are discussed.