Inhibiting the NHE6 gene abolished the formation of amyloid-beta plaques in mouse models of Alzheimer's disease.
Researchers have successfully neutralized a genetic risk factor found in up to 80% of Alzheimer's patients. The ability to neutralize ApoE4 could help in the development of a vaccine, as well as other therapeutics, for late onset Alzheimer's.
Mutations of a gene associated with some forms of autism in humans can hinder the correct growth and connectivity of neurons in mice. This understanding allowed researchers to restore proper neuronal growth in the mice.
