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NF2

Image shows brain scan of a meningioma brain tumor.

Brain Cancer Featured Genetics Neuroscience Videos Open Neuroscience Articles

·August 6, 2017·4 min read

Mapping Mutations That Drive Tumors in Childhood Cancer Survivors

Researchers have identified a specific rearrangement involving the NF2 gene that appears to cause radiation induced meningiomas. The Nature Communication study reports this mutation could be a basis for why many long term pediatric cancer survivors go on to develop brain tumors later in life.

Brain Cancer Featured Genetics Neurology

·July 10, 2017·6 min read

Research Offers Hope For NF2 Neuro-Tumor Patients

Researchers from the University of Plymouth have discovered the tole PrPC plays in the development of neurofibromatosis 2 tumors. According to the study, the prion protein is overproduced in schwannomas, compared with healthy Schwann cells. This overproduction is a result of Merlin deficiency and contributed to tumor growth in NF2 patients.

Brain Cancer Featured Genetics Neurology

·October 10, 2016·5 min read

Researchers Map Genomic Landscape of Schwannoma Brain Cancer

A new study describes the genomic landscape of schwannoma brain cancers.

The image shows a cross section slice of a NEUROFIBROMATOSIS 2 Bilateral schwannomas from a patient.

Featured Neurology

·March 5, 2013·2 min read

Research Leads to Better Understanding of Peripheral Neuropathy

Researchers identify the role of the tumor suppressor Merlin in regulating the integrity of axons. Damage to the axons may result in peripheral neuropathy.

The image shows scans of brains with tumors.

Brain Cancer Featured

·January 25, 2013·3 min read

Genetic Landscape of Common Brain Tumors Holds Key to Personalized Treatment

Researchers discover the genetic landscape of the most common form of brain tumor can be explained by abnormalities in five genes. The finding could help to develop personalized medical therapies and treatment options.