High-frequency repetitive transcranial magnetic stimulation (rTMS) activates MAP2K signaling and enhanced axon regeneration and functional recovery following spinal cord injury.
Researchers engineered cells containing customized adhesion molecules that bind to specific cell partners in predictable ways to form complex multicellular entities. The discovery is a major step toward building new tissue and organs.
Researchers have identified two proteins that prevent the formation of scars in the brain and help promote the regeneration of new neural tissue.
Oxytocin, a hormone connected with bonding and love, could help to heal damage following a heart attack. Researchers found oxytocin stimulates stem cells from the heart's outer layer and migrates into the middle layer where it develops into muscle cells that generate heart contractions. This could be used to promote the regeneration of heart cells following a heart attack.
Using zebrafish, researchers investigated the timing and genetic programming of macrophages that help repair and regenerate the sensory organs within the fish. The findings could help pave the way for regenerative treatments for spinal cord injuries, hearing loss, and heart disorders in humans.
LIN28, a molecule that regulates cell growth could help in the treatment of spinal cord injury and optic nerve damage. When expressed above normal levels, the molecule fuels axon growth in mice with injury, enabling the body to repair damaged nerves.
Enhancing mitochondrial transportation and cellular energetics could help promote regeneration and function following spinal cord injury.
Skin-related stem cells may be key to helping restore the myelin sheath in patients with multiple sclerosis. Using mouse models, researchers discovered melanocyte stem cells can, under the right conditions, function as cells that create myelin.
Researchers have successfully rejuvenated stem cells in the brains of aging mice. The study reports the rejuvenated stem cells help improve regeneration of injured or diseased brain areas.
Researchers have successfully restored the ability to walk in mice paralyzed as a result of spinal cord injuries with the help of a small molecular compound.