LIN28, a molecule that regulates cell growth could help in the treatment of spinal cord injury and optic nerve damage. When expressed above normal levels, the molecule fuels axon growth in mice with injury, enabling the body to repair damaged nerves.
Enhancing mitochondrial transportation and cellular energetics could help promote regeneration and function following spinal cord injury.
Skin-related stem cells may be key to helping restore the myelin sheath in patients with multiple sclerosis. Using mouse models, researchers discovered melanocyte stem cells can, under the right conditions, function as cells that create myelin.
Researchers have successfully rejuvenated stem cells in the brains of aging mice. The study reports the rejuvenated stem cells help improve regeneration of injured or diseased brain areas.
Researchers have successfully restored the ability to walk in mice paralyzed as a result of spinal cord injuries with the help of a small molecular compound.
Researchers have successfully used stem cell therapy to regenerate neurons in damaged areas of zebra fish spinal cords. The treatment helped to restore movement following SCI. The findings raise the possibility of developing new treatments for humans suffering paralysis as a result of spinal cord injury.
Researchers at Boston Children's Hospital have developed a therapeutic cocktail of molecules that restored fine motor skills in mice with spinal cord injuries. When applied to mice who had experienced stroke symptoms, researchers observed increased axon sprouting in subcortical areas.