As with other psychedelics, salvinorin A increased activity across the brain. However, salvinorin A use resulted in more random and disconnected signaling in the default mode network, a brain network associated with relaxing and daydreaming.
Two doses of psilocybin in combination with therapy rapidly and significantly reduces symptoms in those with major depressive disorder. The effects appear to last for up to four weeks.
Working memory system disruptions can cause smokers who quit to relapse within days, a neuroimaging study finds.