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neuropharmacology

This shows the structure of the compound

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·May 29, 2019·4 min read

New compounds could be used to treat autoimmune disorders

Researchers have developed small molecules that inhibit one of the main enzymes implicated in autoimmune response. The research could lead to potential new medications for a range of autoimmune diseases.

Featured Neuroscience Psychology

·May 24, 2019·2 min read

Short-term use of opioids increases subjective pleasure

Short-term opioid use increases positive emotional experiences by intensifying feelings of pleasure and weakening negative emotions. This, researchers say, could be a contributing factor for later opioid addiction. However, the long term use of opioids alters the reward system, diminishing the initial sensitivity and blunting emotions.

Featured Neurology Neuroscience Open Neuroscience Articles

·May 22, 2019·5 min read

Aspirin green light for brain bleed stroke patients

Aspirin may help reduce further bleeding in those who have suffered a stroke.

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Featured Neuroscience Psychology

·May 21, 2019·5 min read

CBD reduces craving and anxiety in people with heroin use disorder

CBD reduces craving and anxiety in those with heroin use disorder during withdrawal from the drug. There were no serious adverse reactions, or impairments to cognition noted with the administration of CBD. Researchers suggest cannabidiol may be useful in helping to combat opioid addiction.

Featured Neuroscience Open Neuroscience Articles Psychology

·May 21, 2019·5 min read

Study supports effectiveness of new fast-acting antidepressant, esketamine nasal spray

Esketamine combined with antidepressants acts rapidly to help alleviate symptoms in those with treatment-resistant depression.

Featured Genetics Neurology Neuroscience Psychology

·May 16, 2019·5 min read

Is the brain parasite Toxoplasma manipulating your behavior, or is your immune system to blame?

Immune system response to chronic infection may be more directly to blame for health and behavioral changes associated with Toxoplasma gondii infections.

this shows the effect of antibiotic treatment on ab in mouse models

Featured Neurology Neuroscience Open Neuroscience Articles

·May 16, 2019·4 min read

Antibiotic treatment alleviates Alzheimer’s disease symptoms in male mice

Study reports specific gut bacteria can influence the development of Alzheimer's disease. In mouse models, long term antibiotic treatment reduced inflammation and the formation of amyloid plaques. However, the reduction was only seen in males. Additionally, the antibiotic treatment altered the activation of microglia in the male mouse models.

Featured Neurology Neuroscience

·May 15, 2019·2 min read

Ragweed compounds could protect nerve cells from Alzheimer’s

Compounds derived from common ragweed may help in the fight against Alzheimer's disease. Researchers report when two of the most active compounds were added to a sample of neurons producing amyloid beta, 20% more cells survived than without exposure.

This shows the outline of a head and brain

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·May 14, 2019·4 min read

Probiotic-derived molecule may suppress fatal brain inflammation

Capsular polysaccharide A (PSA), an envelope molecule, may help to boost the immune system and protect against potentially fatal neuroinflammation associated with Herpes Simplex Encephalitis (HSE). Mice given PSA survived exposure to a lethal herpes simplex viral infection, while those not treated with the probiotic did not, despite both groups being treated with a common antiviral used to treat HSE.

Featured Neurology Neuroscience

·May 10, 2019·6 min read

Statins’ potential to treat MS unrelated to lowering cholesterol

The common statin drug Simvastatin reduces brain atrophy and slows the progression of secondary progressive multiple sclerosis (SPMS). The effects appear to be independent of the drug's cholesterol-lowering effects.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·May 3, 2019·4 min read

New method developed to target cause of Parkinson’s

Clioquinol, an anti-parasitic medication, overcomes the effect of mutations in the LRRK2 gene associated with Parkinson's disease by restoring the acidity of lysosomes and clearing out protein aggregates.

Featured Genetics Neurology Neuroscience

·May 1, 2019·5 min read

Restoring brain function in mice with symptoms of Alzheimer’s disease

Senolytic drugs administered to mice reduced senescent cells around amyloid plaques by more than 90% and decreased neuroinflammation by 50%. Mice treated with the drug combination also showed improvements in spatial memory, compared to other Alzheimer's model mice who received no treatment. The findings could have positive implications for the treatment of Alzheimer's disease in people with the condition.