MRC1+ macrophages are dysfunctional in animal models of neuropathic pain. Stimulating the expression of the anti-inflammatory protein CD163 reduced signs of neuroinflammation in the spinal cords of mice with neuropathic pain.
Transplanting GABAergic cells derived from human-induced pluripotent stem cells into mice resulted in safe, lasting, and effective relief from extreme neuropathic pain. Researchers hope to begin human testing within five years.
A research group at Hiroshima University observed a potential new target for chronic pain treatment. Further research using this receptor could lead to new, more effective drugs to use in pain-relieving treatment for chronic pain.
Researchers have identified the structure of the human type 2 cannabinoid receptor. The findings, researchers say, can help in the development of new treatments for inflammatory and neurodegenerative diseases.
Researchers report the sensation and emotional experiences of pain are not the same. A new study reveals neurons in the amygdala responsible for negative emotions associated with chronic pain.
A new study reports transcranial alternating current stimulation could help treat chronic back pain. Researchers report tACs enhances alpha oscillations in the somatosensory cortex, reducing pain significantly.
Researchers report THC oil may be beneficial in providing pain relief for those suffering radicular pain, such as sciatica. The study reports marijuana reduces connections between areas of the brain that process sensory signals and emotions.