FeaturedNeurologyNeuroscience·February 28, 2023·3 min readSpinal Cord Stimulation May Help Diabetic NeuropathyHigh-frequency spinal cord stimulation may provide symptom relief to those suffering from diabetic neuropathy.Read More
FeaturedNeurologyNeurosciencePain·January 30, 2023·5 min readCalcium Channels Regulate Neuroinflammation and Neuropathic PainThe Orai1 class of calcium channels regulates sex differences in the functioning of immune cells associated with neuroinflammation and neuropathic pain.Read More
FeaturedNeurologyNeurosciencePain·January 26, 2023·5 min readSupplementation With Amino Acid Serine Eases Diabetes Associated NeuropathyLower levels of serine and glycine were associated with a higher risk of neuropathic pain in mouse models of diabetes. Supplementing the diets of the mice with serine reduced symptoms of neuropathy. Researchers say the findings provide a new way in which to identify people at risk of diabetic neuropathy and a potential treatment option.Read More
FeaturedNeurologyNeurosciencePain·January 10, 2023·5 min readStudy Reveals Mechanism Involved in Neuropathic Pain and Could Help Develop Specific TreatmentStudy reveals the role played by neuropathic pain in dendritic cells in the meninges via an increase in the metabolic kynurenine pathway. When the kynurenine pathway initiated by IDO1 was blocked, neuropathic pain was nullified.Read More
FeaturedNeurologyNeurosciencePain·March 19, 2021·3 min readVirtual Reality Could Help to Reduce Pain for People With Nerve InjuriesVirtual reality can help reduce painful sensations following touch people with nerve damage experience.Read More
FeaturedNeurologyNeurosciencePain·March 4, 2021·4 min readA New Cell Type Implicated in Chronic Pain and InflammationMRC1+ macrophages are dysfunctional in animal models of neuropathic pain. Stimulating the expression of the anti-inflammatory protein CD163 reduced signs of neuroinflammation in the spinal cords of mice with neuropathic pain.Read More
FeaturedNeurologyNeurosciencePain·October 16, 2020·5 min readThe Most Effective Drugs for Common Type of Neuropathic PainA study of four drugs to combat chronic neuropathic pain finds Nortriptyline has the highest efficacious percentage and lowest quit rate.Read More
FeaturedGeneticsNeurologyNeurosciencePain·January 25, 2020·2 min readFirst treatment for pain using human stem cells a successTransplanting GABAergic cells derived from human-induced pluripotent stem cells into mice resulted in safe, lasting, and effective relief from extreme neuropathic pain. Researchers hope to begin human testing within five years.Read More
FeaturedNeurologyNeuroscience·January 5, 2020·3 min readEarly prevention of neuropathic painIntercepting CCL2 with specific antibodies may provide an early intervention for chronic neuropathic pain.Read More
FeaturedNeurologyNeuroscience·March 8, 2019·4 min readNew Target for Chronic Pain Relief Confirmed by ScientistsA research group at Hiroshima University observed a potential new target for chronic pain treatment. Further research using this receptor could lead to new, more effective drugs to use in pain-relieving treatment for chronic pain.Read More
FeaturedNeuroscience·February 27, 2019·4 min readStudy Reveals Structure of the Second Human Cannabinoid ReceptorResearchers have identified the structure of the human type 2 cannabinoid receptor. The findings, researchers say, can help in the development of new treatments for inflammatory and neurodegenerative diseases.Read More
FeaturedNeurologyNeuroscienceOpen Neuroscience ArticlesPain·January 20, 2019·7 min readThe Brain Cells That Make Pain Unpleasant IdentifiedResearchers report the sensation and emotional experiences of pain are not the same. A new study reveals neurons in the amygdala responsible for negative emotions associated with chronic pain.Read More