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          neurodevelopment

          This is a drawing of a toy fox and a child with a speech bubble saying "blicket" and "toy".
          FeaturedNeuroscience
          ·November 21, 2024·8 min read

          Toddlers Use Grammar Hints to Unlock the Meaning of New Words

          Toddlers use subtle grammatical cues in sentences to infer the meanings of new words. Researchers found that children rely on "focus" signals—emphasis or stress in speech—rather than assuming words are mutually exclusive.
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          This shows a pregnant woman.
          FeaturedGeneticsNeurologyNeuroscience
          ·November 21, 2024·5 min read

          Maternal Inflammation May Shape Offspring’s Alzheimer’s Risk

          Maternal immune activity during pregnancy influences memory circuitry in offspring, with sex-specific effects extending into midlife. Elevated immune markers like IL-6 and TNF-a in mothers were linked to adverse brain activity in memory regions, particularly in postmenopausal women, and lower cognitive performance in children.
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          This shows a brain.
          AutismFeaturedGeneticsNeurosciencePsychology
          ·November 21, 2024·4 min read

          Immune System Gene Linked to Hyperactivity, ADHD and Autism

          Researchers have uncovered a link between the immune gene regulator STAT1 and hyperactive behaviors in mice, offering new insights into neurodevelopmental disorders like autism and ADHD. STAT1, vital for infection response, also influences brain cell activity, particularly dopamine neurons involved in motivation and learning. In mice with prolonged STAT1 signaling, hyperactivity and reduced neural activity in key brain regions were observed. The study opens the door to targeting STAT1 for potential therapies to address neurobehavioral disorders.
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          This shows a brain and leaves.
          FeaturedNeurosciencePsychology
          ·November 21, 2024·4 min read

          Cannabis Worsens Brain Connectivity Deficits in Psychosis Risk

          Young adults at risk of psychosis show reduced synaptic density, a critical brain connectivity deficit that cannabis use appears to exacerbate, according to new research. The study revealed lower synaptic density linked to social withdrawal and motivational deficits, symptoms poorly addressed by current medications.
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          This shows a brain.
          AutismFeaturedGeneticsNeuroscience
          ·November 20, 2024·6 min read

          Gene Repair Restores Brain Signal Efficiency in Autism

          Autism-linked SHANK3 gene mutations disrupt not only neurons but also oligodendrocytes, essential for producing myelin, which insulates nerve fibers. This damage reduces brain signal efficiency and impairs behavior. Using gene therapy, researchers successfully repaired these cells in a mouse model, restoring their function and myelin production. They validated their findings with human-derived stem cells, confirming similar impairments and repair mechanisms.
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          This shows a child and DNA.
          FeaturedGeneticsNeurosciencePsychology
          ·November 20, 2024·6 min read

          War Impacts Child Development, Alters DNA

          War exposure in Syrian refugee children triggered unique DNA methylation changes, marking genes involved in brain development and stress responses. These epigenetic changes suggest potential long-term effects on health and development, distinct from other traumas like poverty.
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          This shows a baby and a brain.
          FeaturedNeuroscienceOpen Neuroscience Articles
          ·November 19, 2024·4 min read

          Birth Spurs a Surge in Brain Connectivity

          Brain imaging of fetuses and infants reveals a rapid increase in functional brain connectivity at birth, aiding adaptation to the external world. Researchers observed distinct growth patterns, with subcortical, sensorimotor, and superior frontal regions undergoing major reorganizations.
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          This shows two boys.
          FeaturedNeuroscience
          ·November 19, 2024·5 min read

          How Hunter-Gatherer Kids Learn Lifelong Skills by Age Six

          Hunter-gatherer children in the Congo Basin learn critical skills like hunting, gathering, and childcare by age six or seven, thanks to a unique social learning environment. Unlike Western societies, where learning is primarily parent- or teacher-centered, these children gain knowledge from parents, peers, extended family, and unrelated adults within their small, egalitarian communities.
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          This shows a leaf and DNA.
          FeaturedGeneticsNeuroscience
          ·November 15, 2024·6 min read

          Cannabis Use Linked to Epigenetic Changes, Cancer Risk

          Research indicates that cannabis use causes cellular damage that increases the risk of highly cancerous tumors by disrupting mitochondria and damaging DNA. This genotoxicity can result in mutations, accelerated aging, and birth defects, with potential to be passed on to future generations through egg and sperm. Insights from broader mitochondrial research provide a mechanistic understanding of how cannabis affects genetic stability.
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          This shows a pregnant woman and a brain.
          FeaturedNeurologyNeuroscience
          ·November 15, 2024·5 min read

          Antiseizure Drugs in Pregnancy Linked to Neurodevelopmental Risks

          Research suggests that certain antiseizure medications taken during pregnancy may increase the risk of neurodevelopmental conditions in children. Drugs like valproate, topiramate, and carbamazepine were associated with specific risks, including autism and intellectual disability, while lamotrigine was found to pose little to no additional risk.
          Read More
          This shows a brain.
          FeaturedNeuroscienceOpen Neuroscience ArticlesPsychology
          ·November 14, 2024·4 min read

          How Decision-Making Improves with Age

          Adolescents are known for making less optimal, noisy decisions, but a recent study reveals that these tendencies decrease with age and are linked to improvements in complex decision-making skills. Researchers found that decision noise, or variability in choices, mediates age-related gains in goal-directed behaviors and adaptability.
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          This shows the outline of people and brains.
          FeaturedNeurosciencePsychology
          ·November 13, 2024·4 min read

          Metabolic Pathways Link Cannabis to Psychosis in Teens

          A study investigated how cannabis use influences metabolomic patterns linked to psychotic-like experiences in adolescents. Blood samples revealed that non-cannabis users showed inflammatory metabolic changes associated with hallucinations, while cannabis users exhibited shifts in energy-related metabolites tied to brain ketogenesis. These findings suggest that cannabis use may trigger distinct molecular pathways in psychotic-like experiences.
          Read More
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          Disrupted Neuronal Microexons Drive Hyperarousal and Insomnia

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          AI Intelligence Is Not Consciousness

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          Autism Mutations Converge on Shared Early Brain Pathways

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          Rotating Spiral Brain Waves Act as a Space-and-Time Clock

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