New imaging molecule captures brain changes tied to progressive multiple sclerosis
A novel PET neuroimaging tracer detects abnormal inflammation in the cerebral gray matter of patients with secondary progressive multiple sclerosis. ... Read More...
MS
Nanotechnology treatment reverses multiple sclerosis in mice
Extracting nanosized exosomes from bone marrow stem cells and injecting them into mice, researchers reverse symptoms of multiple sclerosis.... Read More...
A new culprit for multiple sclerosis relapses
Injecting extracellular vesicles from healthy mice into mice that had an MS-like disease resulted in the development of a relapse-remitting disease and active CD8+ cells, similar to that seen in human patients with multiple sclerosis. Examining the EVs in mice and humans with MS, researchers identified they contained fibrinogen, a protein normally associated with blood clotting and wound healing. According to researchers, the EVs with fibrinogen appear to activate the CD8+ immune cells. The findings could help with the development of new treatments for RRMS. ... Read More...
Study shows promise in repairing damaged myelin
A study in mouse models of multiple sclerosis demonstrates a compound called sobetirome promotes remyelination, and a derivative of the compound can penetrate the blood-brain barrier to enable a tenfold increase in infiltration to the CNS. Researchers are confident their research will translate from mice into humans, providing a new avenue of treatment for MS.... Read More...
Study of multiple sclerosis patients shows 18 percent misdiagnosed
18% of new patients treated at two Los Angeles hospitals for multiple sclerosis were misdiagnosed with the autoimmune disease. The misdiagnosed patients were often treated unnecessarily with medications designed for MS. From their findings, researchers report the most common alternative diagnosis was migraine. ... Read More...
Do minerals play a role in development of multiple sclerosis?
Study finds no association between mineral levels or dietary mineral intake and an increased risk of multiple sclerosis.... Read More...
Study Reveals New Link Between Food Allergies and Multiple Sclerosis
A new study reveals a link between food allergies and relapses in Multiple Sclerosis.... Read More...
Researchers Create New Map of Brain’s Immune System
Researchers have successfully created a new map of the brain's immune system in both mice and humans. The findings suggest microglia all have the same core signatures, but can act differently, depending on their function. The map also details how the brain's immune system changes as multiple sclerosis progresses.... Read More...
Newly Discovered Immune Cells Play Role in Inflammatory Brain Diseases
Studying animal models, researchers have identified previously unknown types of immune cells that are present in the brains of those with multiple sclerosis. ... Read More...
Old Cells Repair Damage in Brains of Those with Multiple Sclerosis
Researchers discovered oligodendrocyte neurogenesis is limited in the brains of patients with Multiple Sclerosis. However, oligodendrocytes that survive the autoimmune attack associated with MS may be able to form new myelin.... Read More...
Shedding Light on Brain Cell Changes in Multiple Sclerosis
A new study sheds light on brain cells implicated in multiple sclerosis. Researchers found there are several types of oligodendrocytes, and the ratio of these cells differ significantly in those with MS. The findings could help develop new targeted treatments for progressive multiple sclerosis.... Read More...
Discovery Opens New Opportunities to Slow or Reverse Multiple Sclerosis
Researchers report oligodendrocytes may be critical to the remyelination process.... Read More...