FeaturedNeurologyNeuroscience·June 16, 2025·5 min readMitochondrial Link to Cerebellar Decline in MSA new study reveals that mitochondrial dysfunction plays a central role in the loss of Purkinje neurons in the cerebellum, contributing to motor impairments in people with multiple sclerosis (MS). Researchers found that inflammation and demyelination in the cerebellum disrupt the mitochondria—key cellular power sources—leading to energy loss, neuron damage, and ataxia.Read More
FeaturedNeurologyNeuroscience·May 21, 2025·6 min read8-Minute MRI Scan Can Diagnose MS Without Lumbar PunctureA groundbreaking study has shown that multiple sclerosis (MS) can now be accurately diagnosed with a specialized MRI scan, eliminating the need for invasive and often painful lumbar punctures. The scan, which takes just 8 minutes, detects brain lesions centered on veins—a hallmark of MS—using a technique called T2*-weighted MRI.Read More
FeaturedNeurologyNeuroscience·April 29, 2025·4 min readAI Model Detects MS Progression EarlierA new AI model can detect the transition from relapsing-remitting MS to secondary progressive MS much earlier than traditional clinical diagnosis. Using data from over 22,000 patients, the model analyzes routine healthcare information and even indicates its confidence level for each assessment.Read More
FeaturedNeurologyNeurosciencePsychology·April 18, 2025·5 min readDisrupted Myelin Protein Implicated in SchizophreniaA new study has identified the protein hnRNP A1 as a key player in the production and maintenance of myelin, the fatty sheath that insulates nerve fibers in the brain. Myelin loss is common in disorders like multiple sclerosis and schizophrenia, and this research shows that hnRNP A1 disruptions can impair myelination at the molecular level, even before behavioral symptoms appear.Read More
FeaturedNeurologyNeuroscience·April 8, 2025·6 min readAI Tool Tracks MS Brain Changes in SecondsA new AI tool, MindGlide, can rapidly analyze routine brain MRI scans to detect subtle changes caused by multiple sclerosis (MS), such as brain shrinkage and lesions. Traditionally requiring expert interpretation, this process now takes just seconds, allowing more efficient monitoring of disease progression and treatment effects.Read More
FeaturedNeurologyNeuroscience·March 11, 2025·5 min readHow a Common Virus Triggers Brain Attacks in Multiple SclerosisNew research highlights a critical link between antibodies produced against Epstein-Barr virus (EBV) and the development of multiple sclerosis (MS). Scientists discovered that these viral antibodies mistakenly target a protein called GlialCAM in the brain, triggering autoimmune responses associated with MS.Read More
FeaturedNeurologyNeuroscience·February 9, 2023·5 min readNew Biomarker for Disease Progression in Multiple SclerosisThe blood level of the glial fibrillary acidic protein (GFAP) cellular component increases when astrocytes are damaged or activated. Elevated levels of GFAP in the blood can indicate both the current and future progression of multiple sclerosis.Read More
FeaturedNeurologyNeuroscience·October 30, 2021·3 min readVibration Training for Multiple SclerosisVibration training not only improved physical symptoms associated with multiple sclerosis, but it also improved cognitive functions including memory capacity and executive function.Read More
FeaturedGeneticsNeurologyNeuroscience·May 3, 2021·4 min readMini 3D Brain Models Could Speed Up Search for MS TreatmentsA 3D mini brain, created from human skin cells, will be used to study myelin.Read More
FeaturedNeurology·July 28, 2020·3 min readMental Fatigue of Multiple Sclerosis Linked to Inefficient Recruitment of Neural ResourcesThose with MS allocate neural resources less effectively when faced with increased cognitive task demands, and this likely results in the increased mental fatigue those with the neurodegenerative disorder experience.Read More
FeaturedNeurologyNeuroscience·March 28, 2020·3 min readFDA approves ozanimod for treatment of multiple sclerosisThe FDA has approved a new drug named Ozanimod for the treatment of multiple sclerosis. Ozanimod binds to receptors in lymphocytes' surfaces, preventing them from reaching the brain. As the number of active lymphocytes decreases, the attack on the immune system diminishes.Read More
FeaturedNeurologyNeuroscienceOpen Neuroscience Articles·February 26, 2020·4 min readAntioxidant precursor molecule could improve brain function in patients with MSMultiple sclerosis patients who received N-acetylcysteine treatments had improvements in metabolism in brain areas associated with cognition and attention.Read More
