New insight into motor neuron death mechanisms could be a step toward ALS treatment
When a motor neuron-specific pool of heat shock protein 90 (Hps90) was inhibited, motor neuron apoptosis was triggered.... Read More...
motor neurons
The surprising link between a babies’ weeble-wobble and the genetics of motor control
A new fruit fly study reveals a simple genetic system is behind complex movements. The finding sheds light on motor control issues associated with neurodegenerative diseases.... Read More...
ALS patients may benefit from more glucose
Using fruit fly models of ALS, researchers discover neurons given glucose transform the power source into energy, enabling them to survive longer and function better. ... Read More...
‘Like Looking at a Miracle’: Baby Blossoms Thanks to Gene Therapy For Spinal Muscular Atrophy
Zolgensma, an FDA approved gene therapy, supplements the production of the SMN protein to improve motor neuron function in children with spinal muscular atrophy after just one dose. ... Read More...
Research provides important insight on the brain-body connection
Neurons in the motor cortex of rats fall into two categories, those that are externally focused and relay information to other parts of the body, and those that are internally focused. When inhibition is increased, the externally focused neurons switch to internally focused cells.... Read More...
How ALS progresses on genetic and cellular level revealed by high-res spinal cord study
Changes in gene expression help researchers identify ALS associated pathways and establish the key drivers of motor neuron degeneration in the disease.... Read More...
Potential Therapeutic Target for ALS Revealed
Researchers have identified the gene STMN2 as a novel biomarker and potential drug target for ALS. ... Read More...
Breakthrough in Treatment for Restless Leg Syndrome
Researchers report, in restless leg syndrome, neurons targeting muscles may be responsible. ... Read More...
ADHD May Increase Parkinson’s Risk
A new study reports those with ADHD are at an increased risk of developing Parkinson's disease. The study reveals people with ADHD are twice as likely to develop early onset Parkinson's between the ages of 21-66. Additionally, those who are prescribed stimulant medications to help reduce ADHD symptoms, including Ritalin and Adderal, are at a 6-8 times increased risk of developing Parkinson's.... Read More...
Study Raises Doubts on a Previous Theory of Parkinson’s
A new study questions previous assumption about how Parkinson's disease develops and progresses. ... Read More...
New Technique Helps Uncover Changes in ALS Neurons
A new method reveals some ALS affected neurons display hypo-excitability. Researchers say these changes most likely represent early steps in the disease progression.... Read More...
Researchers Shed New Light on Motor Neuron Death
A new collaborative study has helped researchers to uncover some of the earliest molecular events in ALS.... Read More...