motor neurons

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motor neurons

Featured Genetics Neurology Neuroscience

·February 11, 2023·6 min read

Large-Scale Generation of Muscle-Controlling Nerve Cells From ALS Patients

A person's sex is one of the main drivers of altered gene expression in motor neurons, regardless of whether they were derived from patients diagnosed with ALS. Male ALS stem cells generated significantly more motor neurons than the control group, however, this was not seen in female samples.

Featured Neurology Neuroscience

·February 3, 2023·3 min read

Features That May Make Motor Neurons Vulnerable to ALS

Study links motor neurons' large cell size and supporting structures with genes that underly vulnerability to degeneration associated with ALS.

Featured Neurology Neuroscience

·November 15, 2022·3 min read

Nerve Cell Discovery May Lead to Better Treatment for Diseases of the Nervous System

Findings could have implications for new avenues of research for a range of neurodegenerative diseases including ALS and Alzheimer's.

Featured Neurology Neuroscience

·October 1, 2022·5 min read

New Marker of ALS Outcome Identified

Using MEG neuroimaging, researchers have identified a new marker that can be used to predict the clinical outcomes for those suffering from ALS.

Featured Neuroscience Open Neuroscience Articles

·April 19, 2022·4 min read

Exploring the Surprising Role of Motor System Neurons

Motor system neurons not only control movement, they also incite action.

Featured Genetics Neurology Neuroscience Neuroscience Videos

·April 3, 2022·5 min read

Mutations in Noncoding DNA Are Found to Protect the Brain From ALS

Mutations in the IL18RAP gene reduce inflammation and appears to protect the brain against ALS.

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Featured Neurology Neuroscience

·March 10, 2022·4 min read

Motor Neuron Toxin Associated With ALS Identified

PolyP, an inorganic polyphosphate released by astrocytes in people with ALS and frontotemporal dementia contributes to the signature motor neuron death associated with the disease pathologies.

Featured Neuroscience Open Neuroscience Articles

·July 20, 2021·3 min read

Brain ‘Noise’ Keeps Nerve Connections Young

Study reveals how miniature release events help to keep neurons intact and preserve motor neuron function in aging insects.

Featured Genetics Neurology Neuroscience Neuroscience Business

·June 23, 2021·3 min read

Cedars-Sinai Awarded $11.99 Million for ALS Clinical Trial

Cedars-Sinai has been awarded $11.99 million by California's stem cell agency to launch a clinical trial testing a potential gene and stem cell therapy for amyotrophic lateral sclerosis (ALS).

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Featured Genetics Neuroscience Open Neuroscience Articles

·May 1, 2021·3 min read

Study Identifies Diverse Spectrum of Neurons That Govern Movement

Using single nucleus RNA sequencing, researchers have mapped 21 subtypes of motor neurons in the spinal cords of mice.

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Electrophysiology Featured Neuroscience

·February 17, 2021·6 min read

How Some Neurons Compensate for Death of Their Neighbors

Some neurons have the ability to detect and compensate for neighboring neurons, while others do not. The findings shed new light on synaptic plasticity.

Featured Neuroscience Open Neuroscience Articles

·November 17, 2020·4 min read

Motor Neural Population Activity Patterns Are Different for Reach and Grasp Behaviors

A new study challenges the popular theory of intrinsic, dynamic patterns control motor behaviors. Researchers found neuron population dynamics in the motor cortex are different during reaching and grasping behaviors.

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