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MOR

·June 16, 2020·2 min read

The molecular mechanisms of depression

Study reveals how the brain's opioid system is linked to mood changes associated with depression and anxiety. Neuroimaging revealed, in those with depression, there is a decreased number of opioid receptors in specific areas of the brain.

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·May 29, 2020·3 min read

Age, sex and smoking influence opioid receptor function in the brain

Age, sex, and gender influence the organization of the brain's opioid system. Findings shed light on why there are significant differences between the opioid system on an individual level, and why some are more prone to developing opioid-linked pathologies than others.

Featured Neuroscience Psychology

·October 4, 2019·3 min read

Promising steps towards hope for a treatment for schizophrenia

Mu-opioid receptor (MOR) levels are significantly reduced in the striatum in those with schizophrenia. A lack of MOR system stimulation contributes to negative feelings, such as a lack of motivation and anhedonia, associated with the condition. Increasing MOR levels could help to reduce some of the symptoms of schizophrenia.

Image shows endorphin release in a brain scan.

Featured Neuroscience

·August 24, 2017·3 min read

High Intensity Interval Training Releases Endorphins in the Brain

A PET neuroimaging study reveals high intensity impact training significantly increases endorphin release in brain areas associated with controlling emotion and pain.

Featured Neuroscience Open Neuroscience Articles Psychology

·May 30, 2017·3 min read

Brain Opioids Help Us To Relate To Others

Study reveals how the brain's opioid system modulates response to others in pain.

Featured Neurology

·March 10, 2014·4 min read

Study Identifies New Drug Target for Chronic Touch Evoked Pain

Researchers have identified a subset of neurons which mediate tactile allodynia, a touch evoked pain condition that is resistant to conventional pain medications.