Using human stem cells to develop a brain organoid model, researchers were able to show exposure to a common pesticide synergizes with an autism-linked gene mutation. The study provides clear evidence that genetics and environment may combine to disrupt neurodevelopment.
A 3D mini brain, created from human skin cells, will be used to study myelin.
Using mini-brains grown in the lab, researchers have discovered schizophrenia likely begins toward the end of the first trimester of fetal development. Researchers believe, based on their findings, schizophrenia could potentially be treated in utero.
Researchers converted skin cells from patients with a rare congenital brain defect into pluripotent stem cells to generate brain organoids.
3D 'mini brains' grown from human stem cells are functionally and structurally more similar to real brains than the 2D models currently used, a new study reports.
Researchers report they have successfully developed 'mini-brains' made up of the many neurons and cells in the human brain. The mini brains could allow for better research and reduce the need for animal testing.
In a new paper, researchers describe how to make a mini-brain with low expense and relative ease.