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migraine

This shows a man holding his head in pain.

·June 19, 2025·6 min read

How Sleep Deprivation Amplifies Pain in Migraine

New research reveals that sleep deprivation alters how the brain processes pain in people with migraines. Using EEG and pain stimulation, scientists found that migraine sufferers’ brains respond differently after poor sleep, showing reduced ability to suppress pain signals.

Featured Genetics Neurology Neuroscience

·May 22, 2025·5 min read

Gene Amplifies Brain Sensitivity to Light During Migraines

Researchers have identified a molecule in the brain called NEAT1 that plays a key role in light sensitivity, a common and painful symptom of migraines. NEAT1 disrupts the normal balance of nerve signaling by interfering with microRNA activity, leading to increased levels of a pain-related protein called TRPM3.

Featured Neurology Pain

·April 10, 2025·5 min read

Oral Health Tied to Migraines and Fibromyalgia Pain in Women

Poor oral health is significantly linked to increased migraine, abdominal, and musculoskeletal pain in women, particularly those with fibromyalgia. Researchers identified specific oral microbes associated with higher pain scores, highlighting a potential gut-brain-oral microbiome connection.

Featured Neurology Neuroscience Pain

·July 13, 2024·5 min read

Brain’s Lymphatic System Plays Role in Migraine Pain

Researchers discovered how the protein CGRP affects the brain's lymphatic system, contributing to migraine pain. Their study reveals that CGRP prevents cerebrospinal fluid from draining, influencing migraine attacks. This finding could lead to new therapeutic strategies for migraines. More research is needed to understand the sex differences in migraine prevalence.

This shows a woman surrounded by an aura.

Featured Neurology Neuroscience

·July 8, 2024·5 min read

Pathway for Migraine with Aura Discovered

Researchers have discovered why migraines are often one-sided, revealing that proteins released during aura are carried to pain-signaling nerves via cerebrospinal fluid. This study highlights a novel communication channel between the brain and peripheral sensory nervous system. The findings offer insights into migraine mechanisms and potential new treatments. This breakthrough may lead to better therapies for migraine sufferers.

Featured Neurology Neuroscience

·January 31, 2023·5 min read

Migraine Associated With Increased Risk for Pregnancy Complications

Migraine diagnosis in women prior to pregnancy was linked with an increased risk of complications during pregnancy including preeclampsia, gestational hypertension, and an increased risk of pre-term birth.

Featured Neurology Neuroscience

·January 29, 2023·4 min read

In Search of the Optimal Migraine Relief

Using oral transmucosal delivery of eletriptan hydrobromide delivers faster and more effective relief for migraine sufferers.

Featured Neurology Neuroscience

·November 23, 2022·4 min read

Migraine Brain Changes

A new neuroimaging study identifies migraine sufferers have enlarged perivascular spaces in a brain region called the centrum semiovale.

This shows a woman's head and a drawing of a brain

Featured Neurology Neuroscience

·July 13, 2022·4 min read

Abortion Ban May Mean Denial of Effective Drugs for Women With MS, Migraine and Epilepsy

New abortion bans and restrictions could result in life-threatening consequences for women of childbearing age with epilepsy, multiple sclerosis, and migraine due to restrictions placed on their ability to access life-saving medications. Patients in states with strict abortion restrictions are reporting they are unable to access teratogenic drugs to treat their conditions, including methotrexate, as the medications can induce abortion.

Featured Neuroscience

·July 11, 2022·4 min read

Migraine Drug Effective for Weight Loss

Triptans, drugs commonly prescribed for migraine relief, may be effective for the treatment of obesity. Daily triptan exposure led to reduced food intake and increased weight loss in mouse models.

Autism Featured Neuroscience Open Neuroscience Articles

·June 14, 2022·3 min read

How Epilepsy and Migraine Drug Causes Birth Defects

Valproic acid (VPA), an anti-convulsant medication, can cause birth defects when taken during pregnancy. Researchers identified a molecule called p19Arf that appears to be responsible for VPA's induced senescence in neuroepithelial cells. When exposed to VPA, mice lacking p19Arf did not experience gene expression alterations associated with ASD.