A new clinical trial is underway to test ibudilast, an asthma drug approved in Japan, for the treatment of severe COVID-19. Ibudilast is a MIF inhibitor. MIF is a gene that regulates immune response and is a driver of inflammation which results in the cytokine storm associated with coronavirus.
Researchers from Yale University have discovered tow cytokines that could help explain how some people develop PPMS. They report a simple genetic test could be used to identify those most at risk of developing progressive multiple sclerosis.
Researchers identify new biomarkers associated with multiple sclerosis pathogenesis.
In early Alzheimer's, glycation damages an enzyme that plays a crucial role in immune response and insulin regulation, researchers report.
A new blood test can accurately predict whether a person will respond to common antidepressants.