Transplanting fecal microbiota from young mice to older mice reversed hallmark signs of aging in the gut, brains, and eyes. Transplanting the fecal microbiota from old to young mice had the reverse effect, inducing inflammation in the brain and depleting a key protein associated with healthy vision.
Microbes in the gut influence what an animal chooses to eat. Altering the microbiome resulted in changes to preferred diets.
Hypothalamic neurons directly detect variations in bacterial activity and adapt appetite and body temperature accordingly. The findings demonstrate a direct dialog occurs between the brain and the gut microbiota.
A newly developed probiotic bacteria that can synthesize the dopamine precursor L-DOPA is safe, well-tolerated, and eliminates the side effects associated with L-DOPA use for Parkinson's disease.
Researchers reveal how patients who received fecal transplants showed improvements in bipolar symptoms, as well as reductions in anxiety and ADHD behaviors. Fecal transplants may help in the treatment of a number of mental health disorders.
A specific group of fungi in the intestines may protect against intestinal injury and influence social behaviors.
A small-molecule metabolite produced by gut bacteria in mice, can travel to the brain and alter brain cell function, inducing anxiety behaviors.