Researchers from the University of Plymouth have discovered the tole PrPC plays in the development of neurofibromatosis 2 tumors. According to the study, the prion protein is overproduced in schwannomas, compared with healthy Schwann cells. This overproduction is a result of Merlin deficiency and contributed to tumor growth in NF2 patients.
Researchers identify the role of the tumor suppressor Merlin in regulating the integrity of axons. Damage to the axons may result in peripheral neuropathy.
Johns Hopkins scientists hope discovery will drive drug treatments. Johns Hopkins researchers say they have discovered one of the most...