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Memory

·December 11, 2025·5 min read

Boosting Sleep Ripples Helps Preserve Memories Normally Forgotten

A new study shows that precisely manipulating brain activity during sleep can help mice retain memories that would normally fade, offering a potential pathway for treating memory loss conditions. Researchers identified a specific sleep-related pattern—large sharp-wave ripples—that signals when new experiences are being transferred from the hippocampus to the neocortex for long-term storage. By boosting these ripples at just the right moment using optogenetics, scientists enabled mice to remember brief encounters they would typically forget.

Featured Genetics Neuroscience

·December 9, 2025·7 min read

Key Brain Protein Controls How We Learn Reward Cues

Changing levels of the brain protein KCC2 can alter how reward associations form, reshaping the learning process that links cues to outcomes. Reduced KCC2 activity increased dopamine neuron firing and strengthened new cue–reward connections, offering insight into how addictions and maladaptive habits develop.

Featured Neuroscience

·December 5, 2025·6 min read

Why Memories Change: How the Brain Rewrites the Past

A new review explores how episodic memories are formed, stored, and reshaped over time, revealing why our recollections of past events often change. Rather than functioning like fixed files, memories consist of multiple components that can lie dormant until triggered by environmental cues.

Featured Neuroscience

·December 4, 2025·5 min read

Your Next Breath Could Decide What You Remember

The simple act of breathing shapes how and when memories are successfully retrieved. Participants recalled learned word-image pairs more accurately when reminder cues were presented during or just before inhalation, while the brain’s actual reconstruction of the memory occurred during exhalation.

This shows a child reaching to touch neurons.

Featured Genetics Neuroscience

·December 3, 2025·6 min read

Early-Life Stimulation Switches On a Molecular Code for Memory

New research shows that childhood environments shape lifelong memory through a single molecular switch that controls learning-related gene activity. In animal models, enriched early experiences activated this switch, strengthening neural circuits involved in memory and cognition, while deprived environments suppressed it.

Featured Genetics Neuroscience

·December 3, 2025·7 min read

Hidden Brain Layers Revealed in Key Memory Center

Scientists have identified a previously unseen layered organization inside one of the brain’s most important memory hubs. The CA1 region of the hippocampus was found to contain four distinct bands of neuron types, each defined by unique genetic signatures that shift subtly across the structure.

Featured Neuroscience

·December 2, 2025·6 min read

Tiny Cells Shape Memory, Mood, and Behavior

Scientists have uncovered a biological “blueprint” that shows how the brain’s smallest building blocks create the large networks that drive thought, emotion, and behavior. By combining brain imaging with genetic and molecular data, the team demonstrated that cellular and chemical patterns directly shape functional brain networks.

Featured Neuroscience

·November 26, 2025·8 min read

Brain Uses Molecular Timers to Decide What We Remember

New research shows that long-term memory is not stored by a single molecular switch, but by a sequence of timed genetic programs unfolding across different brain regions. Using a virtual-reality learning model in mice, scientists found that experiences are promoted or demoted through multiple biological “durability gates.”

Featured Neuroscience

·November 26, 2025·9 min read

Brain Rebuilds New Skills Using “Cognitive LEGO Blocks”

New research reveals that the brain’s flexibility comes from its ability to reuse “cognitive building blocks” across many tasks, allowing rapid adaptation with minimal relearning. By studying monkeys performing a set of related categorization tasks, researchers found that the prefrontal cortex combines and recombines shared neural patterns like components in a modular system.

This illustration shows a group of overweight people.

Featured Neurology Neuroscience

·November 25, 2025·8 min read

Young Adults With Obesity Show Early Signs of Brain Stress

New research shows that young adults with obesity already display biological patterns associated with liver stress, chronic inflammation, and early neural injury—changes typically seen in older adults with cognitive impairment. Participants with obesity also had unusually low blood choline levels, a nutrient critical for liver function, inflammation control, and long-term brain health.

This shows a brain with a night and day background.

Featured Neuroscience

·November 13, 2025·6 min read

Brain Learning Power Peaks at Specific Times of Day

A new study reveals that the brain’s responsiveness and capacity for learning shift with the time of day, governed by molecules like adenosine that link metabolism, sleep, and neural signaling. Using optogenetics, researchers found that identical stimuli activated brain cells differently at sunrise versus sunset, suggesting that neuronal excitability and plasticity follow daily rhythms.

This shows a family and the face of an older woman.

Featured Neurology Neuroscience

·November 10, 2025·7 min read

Why Alzheimer’s Patients Forget Loved Ones

Researchers have discovered that the heartbreaking moment when a person with Alzheimer’s no longer recognizes family may stem from the breakdown of perineuronal nets, protective structures that support social memory. In mice, the loss of these nets erased memory of familiar individuals while sparing object memory, mirroring early human symptoms.

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Memory

Boosting Sleep Ripples Helps Preserve Memories Normally Forgotten

Key Brain Protein Controls How We Learn Reward Cues

Why Memories Change: How the Brain Rewrites the Past

Your Next Breath Could Decide What You Remember

Early-Life Stimulation Switches On a Molecular Code for Memory

Hidden Brain Layers Revealed in Key Memory Center

Tiny Cells Shape Memory, Mood, and Behavior

Brain Uses Molecular Timers to Decide What We Remember

Brain Rebuilds New Skills Using “Cognitive LEGO Blocks”

Young Adults With Obesity Show Early Signs of Brain Stress

Brain Learning Power Peaks at Specific Times of Day

Why Alzheimer’s Patients Forget Loved Ones

AI Brain Model Reveals How Fear Works in Real Life

Blood Transfusions May Accelerate Alzheimer’s Progression

Boosting Sleep Ripples Helps Preserve Memories Normally Forgotten

Stress Levels Predict Cannabis Use

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