STAT3 plays a crucial role in the serotonergic system as a molecular mediator for controlling emotional reactivity. The findings establish a link between the immune system, serotonergic transmission, and affective disorders such as depression.
Researchers hypothesize vitamin B1 (thiamine) deficiency may play a significant role in dementia associated with alcohol use disorder. It is known iron deposits in the brain contribute to neurodegenerative diseases. Those with AUD have elevated levels of both iron in their blood and thiamine deficiency. Thiamine is vital for maintaining the blood-brain barrier. Thiamine deficiency associated with AUD disrupts the integrity of the BBB, allowing for more iron deposits within the brain and leading to oxidative tissue damage.
Episodic exposure to nicotine, caffeine, and amphetamines triggers malfunctions in the fetal brain, specifically affecting the development of the indusium griseum.
When pregnant women consume diets high in polyunsaturated omega-6 fatty acids, an excess of endocannabinoids is produced which overloads the fetus, and impairs healthy brain development.
The popular Netflix show "13 Reasons Why" has been linked to an increase in suicides in females between the ages of 10 and 19. Researchers said the numbers grew significantly within 3 months of the show's release.
A new study reports neural activity in the prefrontal cortex reacts as though every experience is brand new, even if the event is similar to ones that have previously occurred. Researchers say this could account for feelings of déjà vu.
Researchers have identified new subtypes of neurons in the hypothalamus and determined the function of a dopamine neuron.