Study identifies potential new drugs that can help treat depression and anxiety disorders without many of the adverse effects of other medications currently under evaluation.
The autonomic nervous system has the ability to spontaneously restore muscle function following nerve injury.
Female mice who have not been pregnant or given birth show activation in the anterior cingulate cortex when they acquire maternal behaviors after exposure to pups. The findings reveal through repeated exposure to pups, virgin female mice are capable of learning maternal behaviors that resemble those of mothers following birth.
Researchers identified a molecularly-defined cell population in the hypothalamus that causes a shift in the sleep-wake cycle as a result of exposure to psychostimulants.
Multiple sclerosis-associated retinal layer thinning predicts the severity of future relapses and the likelihood of disability.
STAT3 plays a crucial role in the serotonergic system as a molecular mediator for controlling emotional reactivity. The findings establish a link between the immune system, serotonergic transmission, and affective disorders such as depression.
Researchers hypothesize vitamin B1 (thiamine) deficiency may play a significant role in dementia associated with alcohol use disorder. It is known iron deposits in the brain contribute to neurodegenerative diseases. Those with AUD have elevated levels of both iron in their blood and thiamine deficiency. Thiamine is vital for maintaining the blood-brain barrier. Thiamine deficiency associated with AUD disrupts the integrity of the BBB, allowing for more iron deposits within the brain and leading to oxidative tissue damage.
Episodic exposure to nicotine, caffeine, and amphetamines triggers malfunctions in the fetal brain, specifically affecting the development of the indusium griseum.
When pregnant women consume diets high in polyunsaturated omega-6 fatty acids, an excess of endocannabinoids is produced which overloads the fetus, and impairs healthy brain development.