A neuroimaging study reveals distinctive changes in white matter and other brain tissue physiology in Lyme disease patients during the post-treatment phase. The study also found unusual activity in the frontal lobe, a brain area associated with memory recall and concentration in those who had been treated for Lyme.
The remnants of the Lyme causing B. burgdorferi bacteria may be responsible for the neuroinflammation associated with long-term Lyme disease symptoms. Researchers say the remnants are more inflammatory than the live bacteria.
People with no prior mental health diagnosis who contract Lyme disease have a 42% higher risk of developing an affective disorder, such as depression, and a 75% higher rate of death by suicide than those without the disease.
NapA, a protein associated with the peptidoglycan of Borrelia burgdorferi, plays an amplifying role in causing inflammation in Lyme disease associated arthritis.
Researchers have identified specific anti-bodies that can have a neutralizing effect on the virus responsible for tick-borne encephalitis. Preliminary response in using the anti-bodies in mice has proven affected in preventing TBE. It is hoped a vaccine candidate for TBE can be developed for humans.
Mouse study reveals the antibiotic azlocillin completely kills off the Borrelia burgdorferi bacteria at the onset of Lyme disease. Findings also suggest the drug could be effective for treating patients infected with drug-tolerant bacteria that may cause lingering symptoms.
Ethnobotanical plant extracts, including Ghanaian quinine and Japanese knotweed, show strong activity against B.burgdorferi, outperforming current antibiotics for the treatment of Lyme disease.
Researchers have discovered six candidate biomarkers for Lyme disease. A newly developed test can help identify the disease which, until now, has been notoriously difficult to detect.
A new neuroimaging study reveals 12 people with documented post-treatment Lyme disease syndrome have an elevation of a chemical marker associated with neuroinflammation. The findings could help develop new treatments for the pain, fatigue and brain fog associated with PTLDS.
Researchers have developed new techniques which are able to diagnose Lyme disease bacteria weeks sooner than currently available tests.
A new study reports prediabetes may be more damaging to motor nerves than previously believed.
Engineers have developed a new device that can significantly reduce the cost of testing for diseases such as HIV and Lyme disease. The Lab on a Chip technology may also be used to promote central nervous system research.