A novel protein folding mechanism in the endoplasmic reticulum is essential for long-term memory storage. This mechanism is impaired in tau-models of Alzheimer's disease, but restoring the protein folding mechanism reverses memory impairment associated with dementia.
Study reveals how the CA2 region of the hippocampus plays a key role in long-term memory consolidation.
Long-term memory consolidation and short-term memory processes that occur during sleep do so at a cost to one another.
Reduction of semantic memory could be an indicator of Alzheimer's disease 12 years before onset. Researchers examine different types of memory loss associated with dementia.
Mouse study reveals intermittent fasting improves long-term memory retention and promotes hippocampal neurogenesis. The findings could help to slow cognitive decline in older adults.
Mouse study reveals how neurons reorganize following experiencing novel stimuli. The study reports a possible mechanism for memory consolidation and recall, shedding new light on the biological underpinnings for long-term memory.
Study implicates the mps-2 gene in the formation of long-term memory.
Fruit fly study reveals suppression of a genetic switch boosts long-term memory.
A single insulin-like molecule produces in the nervous system of the marine mollusk Aplysia californica strengthens connections between neurons, enhancing long term memory.