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long COVID

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Featured Neurology Neuroscience Open Neuroscience Articles

·January 23, 2025·7 min read

Long COVID Impairs Exercise Capacity and Cognition for Years

A study of nearly 1,000 people with post-COVID-19 syndrome (PCS) revealed that two-thirds still experienced significant symptoms, including reduced exercise capacity and cognitive performance, two years after infection. Persistent symptom clusters included fatigue, neurocognitive disturbances, and post-exertional malaise, with worse outcomes in individuals with obesity, lower education, or severe initial infections.

This shows a man's head and the covid virus.

Featured Neuroscience

·January 6, 2025·5 min read

Extended Paxlovid May Relieve Long Covid Symptoms

Extended courses of Paxlovid may alleviate symptoms in some patients with long Covid, though its effectiveness varies widely. Of 13 patients studied, five experienced sustained improvements, while others reported temporary or no benefits.

Featured Neurology Neuroscience

·December 4, 2024·6 min read

Most Teens Recover From Long Covid Within Two Years

A large study tracking young people with long Covid found that 70% of those affected had recovered within two years, though 30% continued to experience symptoms. Researchers analyzed data from over 12,000 participants, defining long Covid as experiencing multiple symptoms like fatigue and headaches alongside functional impairments.

Featured Genetics Neurology Neuroscience

·November 29, 2024·5 min read

Spike Protein Lingers in Brain, Fuels Long COVID

A new study reveals that the SARS-CoV-2 spike protein remains in brain-protective tissues and skull bone marrow for years after infection, potentially driving long COVID's neurological symptoms. Using advanced imaging, researchers discovered elevated spike protein levels in these regions, leading to chronic brain inflammation and increased risks of neurodegenerative conditions.

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Featured Neurology Neuroscience

·November 25, 2024·5 min read

TENS Nerve Stimulation Ease Long Covid Pain and Fatigue

A new study demonstrates that a wearable Transcutaneous Electrical Nerve Stimulation (TENS) device can significantly reduce pain, fatigue, and mobility issues in people with long COVID. Participants using the active TENS device reported 26.1% greater pain relief and improved walking performance compared to a placebo group after four weeks of daily use.

Featured Neurology Neuroscience

·November 9, 2024·6 min read

AI Tool Reveals Long COVID May Affect 23% of People

A new AI tool identified long COVID in 22.8% of patients, a much higher rate than previously diagnosed. By analyzing extensive health records from nearly 300,000 patients, the algorithm identifies long COVID by distinguishing symptoms linked specifically to SARS-CoV-2 infection rather than pre-existing conditions. This AI approach, known as "precision phenotyping," helps clinicians differentiate long COVID symptoms from other health issues and may improve diagnostic accuracy by about 3%.

Featured Neurology Neuroscience

·October 14, 2024·6 min read

Persistent Virus May Drive Long COVID

A study found people with long COVID symptoms were twice as likely to have lingering SARS-CoV-2 proteins in their blood, suggesting a persistent viral reservoir may drive some ongoing symptoms. Researchers analyzed blood from 706 individuals and found that 43% of those with multisystem long COVID symptoms had viral proteins present months post-infection, compared to 21% of those without symptoms. This discovery hints at potential benefits from antiviral treatments for those with persistent symptoms. However, the study also reveals that not all long COVID cases show persistent viral proteins, indicating other causes may contribute to this complex condition.

Featured Neurology Neuroscience

·October 8, 2024·5 min read

Brainstem Inflammation Linked to Long-Covid Symptoms

New research shows that severe Covid-19 infection can cause inflammation in the brainstem, potentially leading to prolonged symptoms like fatigue, breathlessness, and anxiety. Using ultra-high-resolution 7-Tesla MRI scanners, scientists observed specific brainstem areas associated with these symptoms, highlighting how immune response post-infection might affect brain health.

This shows the outline of a person and COVID.

Featured Neurology Neuroscience

·October 4, 2024·6 min read

COVID-19 Affects Memory and Cognition for Up to a Year

Healthy adults who contracted COVID-19 had subtle but measurable declines in memory and cognitive performance lasting up to a year. These differences were found through sensitive testing under controlled conditions, though all scores remained within normal ranges, and none of the participants reported lasting cognitive symptoms.

Featured Neurology Neuroscience

·September 24, 2024·5 min read

Cognitive Impacts of COVID Equivalent to 20 Years of Brain Aging

A new study reveals that 12-18 months after hospitalization for COVID-19, patients show significant cognitive decline comparable to 20 years of aging. MRI scans and blood tests also show brain injury markers and reduced brain volume in these patients. The findings suggest that COVID-19 has lasting effects on brain health, even in those without neurological complications.

Featured Neurology Neuroscience

·August 27, 2024·6 min read

COVID’s Inflammation Linked to Long-Term Brain Effects

New research uncovers how COVID-19 may cause neuroinflammation, leading to persistent neurological symptoms even after recovery. The study found elevated levels of pro-inflammatory cytokines and significant changes in cerebrospinal fluid among hospitalized patients, highlighting the brain's vulnerability to the virus.

Featured Neurology Neuroscience

·August 23, 2024·3 min read

COVID’s Spike Protein Enhances Ability to Infect Brain

Researchers have discovered a mutation in the SARS-CoV-2 spike protein that enhances its ability to infect the central nervous system, potentially explaining neurological symptoms and “long COVID.” The mutation was found to allow the virus to better infiltrate the brain, with implications for future treatments targeting COVID-19’s effects on the brain. The findings highlight the need for specific therapies to address these neurological complications.

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long COVID

Long COVID Impairs Exercise Capacity and Cognition for Years

Extended Paxlovid May Relieve Long Covid Symptoms

Most Teens Recover From Long Covid Within Two Years

Spike Protein Lingers in Brain, Fuels Long COVID

TENS Nerve Stimulation Ease Long Covid Pain and Fatigue

AI Tool Reveals Long COVID May Affect 23% of People

Persistent Virus May Drive Long COVID

Brainstem Inflammation Linked to Long-Covid Symptoms

COVID-19 Affects Memory and Cognition for Up to a Year

Cognitive Impacts of COVID Equivalent to 20 Years of Brain Aging

COVID’s Inflammation Linked to Long-Term Brain Effects

COVID’s Spike Protein Enhances Ability to Infect Brain

Modified FDA Drug Blocks Pediatric Brain Tumor Relapse

Blood Proteins Identified That Predict Multiple Sclerosis Early

Gene Therapy Proven to Shield Brain from TDP-43 Damage

Estrogen Loss May Drive Female Alzheimer’s

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