FeaturedNeurologyNeuroscienceOpen Neuroscience Articles·May 30, 2021·4 min readDiscovery May Point to Parkinson’s Disease TherapiesIn Parkinson's disease, alpha-synuclein binds to LC3B. Normally, LC3B causes misfolded proteins to become degraded, but in the case of Parkinson's, LC3B becomes trapped in protein aggregates and becomes inactive.Read More
FeaturedGeneticsNeuroscienceOpen Neuroscience Articles·July 19, 2019·3 min readTaking out the Protein Garbage Becomes More Difficult as Neurons AgeIn aging mice, the number of autophagosomes is significantly decreased, and pronounced defects in the structure of autophagosomes increased. Turning on the WIPI2B protein restores autophagosome formation in aged neurons.Read More
