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          kynurenine pathway

          This shows a person holding a brain model.
          FeaturedNeurologyNeuroscience
          ·August 25, 2024·6 min read

          Blocking a Brain Pathway Reverses Memory Loss in Alzheimer’s

          Blocking the kynurenine pathway, a regulator of brain metabolism, can restore cognitive function in lab mice with Alzheimer’s disease. The pathway is overactivated in Alzheimer’s, disrupting glucose metabolism and starving neurons of energy. By inhibiting this pathway, researchers improved memory and brain plasticity in mice, offering hope for new treatments in humans. IDO1 inhibitors, currently in cancer trials, could be repurposed for Alzheimer’s treatment.
          Read More
          This shows a red brain
          FeaturedGeneticsNeuroscienceOpen Neuroscience ArticlesPsychology
          ·April 10, 2019·5 min read

          Inflammation linked to chemical imbalance in schizophrenia

          Increased kynurenic acid production has been implicated in the pathology of schizophrenia. The findings provide a new target for cell-specific treatments that help reduce the production of kynurenic acid and reduce symptoms of schizophrenia.
          Read More

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          This shows an ear.

          Gene Therapy Restores Hearing in Those with Deafness

          This shows a brain.

          Forever Chemicals May Disrupt Brain Development

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          Kids Outsmart AI in Puzzle Game That Builds Critical Thinking

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          Drug-Coated Neural Implants Reduce Immune Rejection

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