Multiple sclerosis patients who followed a ketogenic diet experienced less fatigue, improved symptoms of depression, and improved quality of life. Additionally, those who followed a keto diet had reduced levels of inflammatory markers in blood samples.
K.Vita, a new oral dietary substance based on the ketogenic diet, reduced seizures by up to 50% in children and adults with drug-resistant epilepsy.
In the short term, a ketogenic diet can help improve health as well as assist in weight loss. However, the negative effects of the keto diet start to appear after one week. Mice who were fed a ketogenic-style diet for more than seven days consumed more fat than they could burn, and had an increased risk of developing diabetes and obesity.
A modified Mediterranean-ketogenic diet can modulate the gut microbiome and metabolites associated with improvements in Alzheimer's disease biomarkers.
A small scale pilot study reveals adults with mild cognitive impairment may have improved brain function and memory when they switch to a high-fat, low-carb diet.
Mimicking effects of the ketogenic diet with a drug called 2-DG reduced cell excitation and epileptic activity in mouse models of post-traumatic epilepsy. 2-DG may have the potential to restore network function following TBI, reducing the risk of epilepsy associated with head injuries. The findings may have positive implications for people who developed post-traumatic epilepsy, suggesting a change in diet could help alleviate some symptoms.